Pregabalin and Narcotic intoxication - a phase IV clinical study of FDA data

Summary:

Narcotic intoxication is reported as a side effect among people who take Pregabalin (pregabalin), especially for people who are male, 60+ old, also take Oxycontin, and have Breakthrough pain.

The phase IV clinical study analyzes which people have Narcotic intoxication when taking Pregabalin. It is created by eHealthMe based on reports of 73,056 people who have side effects when taking Pregabalin from the FDA, and is updated regularly.

What is Pregabalin?

Pregabalin has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 74,070 Pregabalin users. Check the latest studies of Pregabalin.

What is Narcotic intoxication?

Narcotic intoxication (a condition caused by use of narcotic agents) is found to be associated with 63 drugs and 236 conditions by eHealthMe. Check the latest studies of Narcotic intoxication.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

73,056 people reported to have side effects when taking Pregabalin.
Among them, 45 people (0.06%) have Narcotic intoxication.

Could Pregabalin cause Narcotic intoxication?

Among these 45 people:

What is the gender of people who have Narcotic intoxication when taking Pregabalin? *

female: 11.11 %
male: 88.89 %

What is the age of people who have Narcotic intoxication when taking Pregabalin? *

What are other drugs people take besides Pregabalin? *

What are other side effects people have besides Narcotic intoxication? *

Acute Kidney Failure: 40 people, 88.89%
Blood Creatine Phosphokinase Increased: 39 people, 86.67%
Drowsiness: 31 people, 68.89%
Miosis (constriction of the pupil of the eye, resulting from a normal response to an increase in light): 31 people, 68.89%
Confusional State: 19 people, 42.22%
Hypophagia (reduced food intake): 14 people, 31.11%
Rashes (redness): 14 people, 31.11%
Dehydration (dryness resulting from the removal of water): 14 people, 31.11%
Hepatic Function Abnormal: 5 people, 11.11%
Renal Impairment (severely reduced kidney function): 5 people, 11.11%

What are the existing conditions these people have? *

Phantom Pain: 40 people, 88.89%
High Blood Cholesterol: 40 people, 88.89%
Fluid Overload (too much fluid in the blood): 40 people, 88.89%
Breakthrough Pain: 40 people, 88.89%
Left Ventricular Failure (left ventricle fails to contract forcefully): 39 people, 86.67%
High Blood Pressure: 36 people, 80.00%
Diabetes: 35 people, 77.78%
Urination - Excessive Volume: 30 people, 66.67%
Musculoskeletal Chest Pain (pain in chest muscle or nerve or bones): 4 people, 8.89%
Mesothelioma (rare type of cancer that occurs in the thin layer of cells lining the body's internal organs, known as the mesothelium): 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Pregabalin and have Narcotic intoxication?

- Check whether Narcotic intoxication is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pregabalin:

Pregabalin (74,070 reports)

Browse all side effects of Pregabalin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Narcotic intoxication:

Narcotic intoxication (63 drugs)

Browse all the conditions that are associated with Narcotic intoxication:

Narcotic intoxication (236 conditions)

Related publications that referenced our studies

de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .
de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on pregabalin (the active ingredients of Pregabalin) and Pregabalin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.