Pregabalin and Paraplegia - a phase IV clinical study of FDA data

Summary:

Paraplegia is reported as a side effect among people who take Pregabalin (pregabalin), especially for people who are female, 50-59 old, also take Hydrocodone, and have Back pain.

The phase IV clinical study analyzes which people have Paraplegia when taking Pregabalin. It is created by eHealthMe based on reports of 73,056 people who have side effects when taking Pregabalin from the FDA, and is updated regularly.

What is Pregabalin?

Pregabalin has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 74,070 Pregabalin users. Check the latest studies of Pregabalin.

What is Paraplegia?

Paraplegia (paralysis of the legs and lower body) is found to be associated with 434 drugs and 536 conditions by eHealthMe. Check the latest studies of Paraplegia.

On Aug, 02, 2026

73,056 people reported to have side effects when taking Pregabalin.
Among them, 37 people (0.05%) have Paraplegia.

Among these 37 people:

What is the gender of people who have Paraplegia when taking Pregabalin? *

female: 56.25 %
male: 43.75 %

What is the age of people who have Paraplegia when taking Pregabalin? *

What are other drugs people take besides Pregabalin? *

Hydrocodone: 11 people, 29.73%
Paracetamol: 10 people, 27.03%
Morphine: 8 people, 21.62%
Actiq: 7 people, 18.92%
Triamcinolone: 5 people, 13.51%
Fentanyl Transdermal System: 4 people, 10.81%
Iopamidol: 3 people, 8.11%
Lidocaine: 3 people, 8.11%
Pantoprazole: 3 people, 8.11%
Mekinist: 2 people, 5.41%

What are other side effects people have besides Paraplegia? *

Extradural Haematoma (traumatic brain injury-collection of blood in the 'potential' space between the skull and the outer protective): 12 people, 32.43%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 9 people, 24.32%
Constipation: 9 people, 24.32%
Spinal Cord Compression: 8 people, 21.62%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 18.92%
Gastric Ulcer (stomach ulcer): 7 people, 18.92%
Disease Progression: 7 people, 18.92%
Pain In Extremity: 7 people, 18.92%
Urinary Retention (the inability to completely or partially empty the bladder): 7 people, 18.92%
Spinal Pain (pain in spine): 6 people, 16.22%

What are the existing conditions these people have? *

Herniated Nucleus Pulposus (Slipped Disk): 7 people, 18.92%
Back Pain: 7 people, 18.92%
Breakthrough Pain: 5 people, 13.51%
High Blood Pressure: 4 people, 10.81%
Sedation: 4 people, 10.81%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 3 people, 8.11%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 8.11%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 8.11%
Type 1 Diabetes: 3 people, 8.11%
Anaesthesia: 3 people, 8.11%

* Approximation only. Some reports may have incomplete information.

Do you take Pregabalin and have Paraplegia?

- Check whether Paraplegia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pregabalin:

Pregabalin (74,070 reports)

Paraplegia treatments and more:

Paraplegia (3,983 reports)

Browse all side effects of Pregabalin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Paraplegia:

Paraplegia (434 drugs)

Browse all the conditions that are associated with Paraplegia:

Paraplegia (536 conditions)

Related publications that referenced our studies

Lee, Y. J., & Park, K. , "Secondary Raynaud’s Phenomenon and Skin Necrosis of Toes in the Paraplegic Patient with Hypertension", Drug safety-case reports, 2018 Jan .
de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .
Lee, Y. J., & Park, K. , "Secondary Raynaud’s Phenomenon and Skin Necrosis of Toes in the Paraplegic Patient with Hypertension", Drug safety-case reports, 2018 Jan .
de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on pregabalin (the active ingredients of Pregabalin) and Pregabalin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.