Prilosec and Transitional cell carcinoma - a phase IV clinical study of FDA data

Summary:

Transitional cell carcinoma is reported as a side effect among people who take Prilosec (omeprazole), especially for people who are male, 60+ old, also take Fish Oil, and have Myelodysplastic syndrome.

The phase IV clinical study analyzes which people have Transitional cell carcinoma when taking Prilosec. It is created by eHealthMe based on reports of 171,578 people who have side effects when taking Prilosec from the FDA, and is updated regularly.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,286 Prilosec users. Check the latest studies of Prilosec.

What is Transitional cell carcinoma?

Transitional cell carcinoma (cancer tumour inner most layer of urinary system) is found to be associated with 186 drugs and 268 conditions by eHealthMe. Check the latest studies of Transitional cell carcinoma.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

171,578 people reported to have side effects when taking Prilosec.
Among them, 13 people (0.01%) have Transitional cell carcinoma.

Could Prilosec cause Transitional cell carcinoma?

Among these 13 people:

What is the gender of people who have Transitional cell carcinoma when taking Prilosec? *

female: 46.15 %
male: 53.85 %

What is the age of people who have Transitional cell carcinoma when taking Prilosec? *

What are other drugs people take besides Prilosec? *

What are other side effects people have besides Transitional cell carcinoma? *

Haematuria (presence of blood in urine): 8 people, 61.54%
Vitreous Floaters (spots before the eyes): 6 people, 46.15%
Urinary Tract Disorder: 6 people, 46.15%
Unilateral Hydronephrosis (kidney stone that causes obstruction of the ureter): 6 people, 46.15%
Retinal Disorder (disease of retina): 6 people, 46.15%
Diarrhea: 6 people, 46.15%
Visual Impairment: 6 people, 46.15%
Terminal State (the transitional states between life and biological death): 5 people, 38.46%
Pneumonia: 3 people, 23.08%
The Flu (the flu is caused by an influenza virus): 2 people, 15.38%

What are the existing conditions these people have? *

Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 6 people, 46.15%
Type 2 Diabetes: 2 people, 15.38%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.69%
Pain: 1 person, 7.69%
Multiple Myeloma (cancer of the plasma cells): 1 person, 7.69%
Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 1 person, 7.69%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 7.69%
High Blood Pressure: 1 person, 7.69%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Prilosec and have Transitional cell carcinoma?

- Check whether Transitional cell carcinoma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prilosec:

Prilosec (175,286 reports)

Browse all side effects of Prilosec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Transitional cell carcinoma:

Transitional cell carcinoma (186 drugs)

Browse all the conditions that are associated with Transitional cell carcinoma:

Transitional cell carcinoma (268 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on omeprazole (the active ingredients of Prilosec) and Prilosec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.