Prilosec and Vitamin b12 increased - a phase IV clinical study of FDA data

Summary:

Vitamin b12 increased is reported as a side effect among people who take Prilosec (omeprazole), especially for people who are female, 50-59 old, also take Folic Acid, and have Pain.

The phase IV clinical study analyzes which people have Vitamin b12 increased when taking Prilosec. It is created by eHealthMe based on reports of 171,578 people who have side effects when taking Prilosec from the FDA, and is updated regularly.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,286 Prilosec users. Check the latest studies of Prilosec.

What is Vitamin b12 increased?

Vitamin b12 increased is found to be associated with 213 drugs and 343 conditions by eHealthMe. Check the latest studies of Vitamin b12 increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

171,578 people reported to have side effects when taking Prilosec.
Among them, 12 people (0.01%) have Vitamin b12 increased.

Could Prilosec cause Vitamin b12 increased?

Among these 12 people:

What is the gender of people who have Vitamin b12 increased when taking Prilosec? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Vitamin b12 increased when taking Prilosec? *

What are other drugs people take besides Prilosec? *

What are other side effects people have besides Vitamin b12 increased? *

Fatigue (feeling of tiredness): 7 people, 58.33%
Haematocrit Decreased: 7 people, 58.33%
Haemoglobin Decreased: 7 people, 58.33%
Blood Glucose Increased: 7 people, 58.33%
Red Blood Cell Count Decreased: 6 people, 50.00%
Carbon Dioxide Decreased: 6 people, 50.00%
Blood Potassium Decreased: 6 people, 50.00%
Nausea (feeling of having an urge to vomit): 6 people, 50.00%
Alanine Aminotransferase Increased: 6 people, 50.00%
White Blood Cell Count Decreased: 5 people, 41.67%

What are the existing conditions these people have? *

Pain: 6 people, 50.00%
Aplastic Anemia: 5 people, 41.67%
Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 5 people, 41.67%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 8.33%
High Blood Cholesterol: 1 person, 8.33%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 8.33%
Depression: 1 person, 8.33%
Dyspnea (difficult or laboured breathing): 1 person, 8.33%
Gait Disturbance: 1 person, 8.33%
Haemochromatosis (body to absorb more iron than usual from food): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Prilosec and have Vitamin b12 increased?

- Check whether Vitamin b12 increased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prilosec:

Prilosec (175,286 reports)

Browse all side effects of Prilosec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Vitamin b12 increased:

Vitamin b12 increased (213 drugs)

Browse all the conditions that are associated with Vitamin b12 increased:

Vitamin b12 increased (343 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on omeprazole (the active ingredients of Prilosec) and Prilosec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.