Primaxin and Cardiac arrest - a phase IV clinical study of FDA data

Summary:

Cardiac arrest is reported as a side effect among people who take Primaxin (cilastatin sodium; imipenem), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Vancomycin, and have Pneumonia.

The phase IV clinical study analyzes which people have Cardiac arrest when taking Primaxin. It is created by eHealthMe based on reports of 4,534 people who have side effects when taking Primaxin from the FDA, and is updated regularly.

What is Primaxin?

Primaxin has active ingredients of cilastatin sodium; imipenem. eHealthMe is studying from 4,540 Primaxin users. Check the latest studies of Primaxin.

What is Cardiac arrest?

Cardiac arrest is found to be associated with 2,226 drugs and 2,513 conditions by eHealthMe. Check the latest studies of Cardiac arrest.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

4,534 people reported to have side effects when taking Primaxin.
Among them, 70 people (1.54%) have Cardiac arrest.

Could Primaxin cause Cardiac arrest?

Among these 70 people:

How long have people been on Primaxin when they have Cardiac arrest? *

  • < 1 month: 85 %
  • 1 - 6 months: 15 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Cardiac arrest when taking Primaxin? *

  • female: 42.86 %
  • male: 57.14 %

What is the age of people who have Cardiac arrest when taking Primaxin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 1.54 %
  • 20-29: 7.69 %
  • 30-39: 3.08 %
  • 40-49: 26.15 %
  • 50-59: 21.54 %
  • 60+: 40.0 %

What are other drugs people take besides Primaxin? *

  1. Vancomycin: 19 people, 27.14%
  2. Heparin: 10 people, 14.29%
  3. Fluconazole: 10 people, 14.29%
  4. Lasix: 8 people, 11.43%
  5. Tylenol: 8 people, 11.43%
  6. Prednisone: 8 people, 11.43%
  7. Magnesium Sulfate: 7 people, 10.00%
  8. Methotrexate: 7 people, 10.00%
  9. Ativan: 6 people, 8.57%
  10. Lisinopril: 6 people, 8.57%

What are other side effects people have besides Cardiac arrest? *

  1. Acute Kidney Failure: 14 people, 20.00%
  2. Hypotension (abnormally low blood pressure): 14 people, 20.00%
  3. Multi-Organ Failure (multisystem organ failure): 12 people, 17.14%
  4. Sepsis (a severe blood infection that can lead to organ failure and death): 12 people, 17.14%
  5. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 8 people, 11.43%
  6. Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 8 people, 11.43%
  7. Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 7 people, 10.00%
  8. Thrombocytopenia (decrease of platelets in blood): 7 people, 10.00%
  9. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 7 people, 10.00%
  10. Consciousness - Decreased: 6 people, 8.57%

What are the existing conditions these people have? *

  1. Pneumonia: 6 people, 8.57%
  2. Infection: 5 people, 7.14%
  3. Sepsis (a severe blood infection that can lead to organ failure and death): 5 people, 7.14%
  4. Pulmonary Tuberculosis (lungs tuberculosis): 3 people, 4.29%
  5. Pain: 3 people, 4.29%
  6. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 3 people, 4.29%
  7. Neuropathy Peripheral (surface nerve damage): 3 people, 4.29%
  8. Diabetes: 3 people, 4.29%
  9. Systemic Candida (whole body fungal infection): 2 people, 2.86%
  10. Gastric Ulcer (stomach ulcer): 2 people, 2.86%

* Approximation only. Some reports may have incomplete information.

Do you take Primaxin and have Cardiac arrest?

- Check whether Cardiac arrest is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Primaxin:

Cardiac arrest treatments and more:

How severe was Cardiac arrest and when was it recovered:

Expand to all the drugs that have ingredients of cilastatin sodium; imipenem:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Primaxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cardiac arrest:

Browse all the conditions that are associated with Cardiac arrest:


How the study uses the data?

The study uses data from the FDA. It is based on cilastatin sodium; imipenem (the active ingredients of Primaxin) and Primaxin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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