Primaxin and Disease progression - a phase IV clinical study of FDA data

Summary:

Disease progression is reported as a side effect among people who take Primaxin (cilastatin sodium; imipenem), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Diflucan, and have Colon cancer.

The phase IV clinical study analyzes which people have Disease progression when taking Primaxin. It is created by eHealthMe based on reports of 4,534 people who have side effects when taking Primaxin from the FDA, and is updated regularly.

What is Primaxin?

Primaxin has active ingredients of cilastatin sodium; imipenem. eHealthMe is studying from 4,540 Primaxin users. Check the latest studies of Primaxin.

What is Disease progression?

Disease progression is found to be associated with 1,795 drugs and 2,257 conditions by eHealthMe. Check the latest studies of Disease progression.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

4,534 people reported to have side effects when taking Primaxin.
Among them, 16 people (0.35%) have Disease progression.

Could Primaxin cause Disease progression?

Among these 16 people:

How long have people been on Primaxin when they have Disease progression? *

What is the gender of people who have Disease progression when taking Primaxin? *

female: 57.14 %
male: 42.86 %

What is the age of people who have Disease progression when taking Primaxin? *

What are other drugs people take besides Primaxin? *

What are other side effects people have besides Disease progression? *

Fever: 3 people, 18.75%
Acute Kidney Failure: 3 people, 18.75%
Multi-Organ Failure (multisystem organ failure): 3 people, 18.75%
Thrombocytopenia (decrease of platelets in blood): 3 people, 18.75%
Pleural Effusion (water on the lungs): 3 people, 18.75%
Hepatic Failure (liver failure): 2 people, 12.50%
Renal Impairment (severely reduced kidney function): 2 people, 12.50%
Haemorrhage Intracranial (bleeding within the skull): 2 people, 12.50%
Dyspnea (difficult or laboured breathing): 2 people, 12.50%
Diarrhea: 2 people, 12.50%

What are the existing conditions these people have? *

Colon Cancer: 2 people, 12.50%
Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 1 person, 6.25%
Staphylococcal Infection (an infection with staphylococcus bacteria): 1 person, 6.25%
Skin Bacterial Infection: 1 person, 6.25%
Sepsis (a severe blood infection that can lead to organ failure and death): 1 person, 6.25%
Pneumonia Primary Atypical (primary atypical pneumonia which were probably caused by mycoplasma pneumoniae): 1 person, 6.25%
Pneumonia Bacterial (pneumonia associated with bacterial infection): 1 person, 6.25%
Mycobacterium Fortuitum Infection (bacterial infection): 1 person, 6.25%
Multiple Myeloma (cancer of the plasma cells): 1 person, 6.25%
Hypotension (abnormally low blood pressure): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Primaxin and have Disease progression?

- Check whether Disease progression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Primaxin:

Primaxin (4,540 reports)

Browse all side effects of Primaxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Disease progression:

Disease progression (1,795 drugs)

Browse all the conditions that are associated with Disease progression:

Disease progression (2,257 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cilastatin sodium; imipenem (the active ingredients of Primaxin) and Primaxin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.