Primaxin and Ileus paralytic - a phase IV clinical study of FDA data

Summary:

Ileus paralytic is reported as a side effect among people who take Primaxin (cilastatin sodium; imipenem), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Prednisone, and have B precursor type acute leukaemia.

The phase IV clinical study analyzes which people have Ileus paralytic when taking Primaxin. It is created by eHealthMe based on reports of 4,534 people who have side effects when taking Primaxin from the FDA, and is updated regularly.

What is Primaxin?

Primaxin has active ingredients of cilastatin sodium; imipenem. eHealthMe is studying from 4,540 Primaxin users. Check the latest studies of Primaxin.

What is Ileus paralytic?

Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles) is found to be associated with 683 drugs and 850 conditions by eHealthMe. Check the latest studies of Ileus paralytic.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

4,534 people reported to have side effects when taking Primaxin.
Among them, 19 people (0.42%) have Ileus paralytic.

Could Primaxin cause Ileus paralytic?

Among these 19 people:

How long have people been on Primaxin when they have Ileus paralytic? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Ileus paralytic when taking Primaxin? *

  • female: 17.65 %
  • male: 82.35 %

What is the age of people who have Ileus paralytic when taking Primaxin? *

  • 0-1: 0.0 %
  • 2-9: 5.88 %
  • 10-19: 5.88 %
  • 20-29: 35.29 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 17.65 %
  • 60+: 35.29 %

What are other drugs people take besides Primaxin? *

  1. Prednisone: 7 people, 36.84%
  2. Zofran: 6 people, 31.58%
  3. Norflex: 6 people, 31.58%
  4. Ativan: 6 people, 31.58%
  5. Carafate: 6 people, 31.58%
  6. Compazine: 6 people, 31.58%
  7. Dalmane: 6 people, 31.58%
  8. Demerol: 6 people, 31.58%
  9. Diflucan: 6 people, 31.58%
  10. Effexor: 6 people, 31.58%

What are other side effects people have besides Ileus paralytic? *

  1. Hypokalemia (low potassium): 6 people, 31.58%
  2. Gallstones (stone formation by bile component): 6 people, 31.58%
  3. Dehydration (dryness resulting from the removal of water): 6 people, 31.58%
  4. Electrolyte Imbalance: 6 people, 31.58%
  5. Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 6 people, 31.58%
  6. Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 6 people, 31.58%
  7. Paraplegia (paralysis of the legs and lower body): 6 people, 31.58%
  8. Suicidal Ideation: 6 people, 31.58%
  9. Hypocalcaemia (levels of calcium in blood serum are abnormally low): 6 people, 31.58%
  10. Oedema Peripheral (superficial swelling): 6 people, 31.58%

What are the existing conditions these people have? *

  1. Febrile Neutropenia (fever with reduced white blood cells): 2 people, 10.53%
  2. B Precursor Type Acute Leukaemia (lymphoid cancer): 2 people, 10.53%
  3. Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Primaxin and have Ileus paralytic?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Primaxin:

Ileus paralytic treatments and more:

How severe was Ileus paralytic and when was it recovered:

Expand to all the drugs that have ingredients of cilastatin sodium; imipenem:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Primaxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ileus paralytic:

Browse all the conditions that are associated with Ileus paralytic:


How the study uses the data?

The study uses data from the FDA. It is based on cilastatin sodium; imipenem (the active ingredients of Primaxin) and Primaxin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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