Cortef and Night sweats - a phase IV clinical study of FDA data

Summary:

Night sweats is reported as a side effect among people who take Cortef (hydrocortisone), especially for people who are female, 50-59 old, also take Synthroid, and have Blood pressure abnormal.

The phase IV clinical study analyzes which people have Night sweats when taking Cortef. It is created by eHealthMe based on reports of 4,132 people who have side effects when taking Cortef from the FDA, and is updated regularly.

What is Cortef?

Cortef has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 4,254 Cortef users. Check the latest studies of Cortef.

What is Night sweats?

Night sweats (sweating in night) is found to be associated with 1,526 drugs and 1,689 conditions by eHealthMe. Check the latest studies of Night sweats.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

4,132 people reported to have side effects when taking Cortef.
Among them, 13 people (0.31%) have Night sweats.

Among these 13 people:

What is the gender of people who have Night sweats when taking Cortef? *

female: 58.33 %
male: 41.67 %

What is the age of people who have Night sweats when taking Cortef? *

What are other drugs people take besides Cortef? *

What are other side effects people have besides Night sweats? *

Headache (pain in head): 10 people, 76.92%
Joint Pain: 8 people, 61.54%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 7 people, 53.85%
Weight Decreased: 6 people, 46.15%
Pain: 6 people, 46.15%
Fatigue (feeling of tiredness): 6 people, 46.15%
Memory Loss: 5 people, 38.46%
Dyspnea (difficult or laboured breathing): 4 people, 30.77%
Nasopharyngitis (inflammation of the nasopharynx): 4 people, 30.77%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 30.77%

What are the existing conditions these people have? *

Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 3 people, 23.08%
Renal Cell Carcinoma (a kidney cancer): 3 people, 23.08%
Pain: 3 people, 23.08%
Blood Pressure Abnormal: 3 people, 23.08%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 15.38%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 15.38%
Depression: 1 person, 7.69%
Blood Growth Hormone Abnormal: 1 person, 7.69%
Breast Cancer: 1 person, 7.69%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Cortef and have Night sweats?

- Check whether Night sweats is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cortef:

Cortef (4,254 reports)

Night sweats treatments and more:

Night sweats (40,332 reports)

Browse all side effects of Cortef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Night sweats:

Night sweats (1,526 drugs)

Browse all the conditions that are associated with Night sweats:

Night sweats (1,689 conditions)

Related publications that referenced our studies

Murday HK, Rusli FD, Blandy C, Vollenhoven B, "Night sweats: it may be hemochromatosis", Climacteric, 2016 Jul .
Murday HK, Rusli FD, Blandy C, Vollenhoven B, "Night sweats: it may be hemochromatosis", Climacteric, 2016 Jul .

How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone (the active ingredients of Cortef) and Cortef (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.