Primaxin and Liver function test abnormal - a phase IV clinical study of FDA data

Summary:

Liver function test abnormal is reported as a side effect among people who take Primaxin (cilastatin sodium; imipenem), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Ativan, and have Cholecystitis.

The phase IV clinical study analyzes which people have Liver function test abnormal when taking Primaxin. It is created by eHealthMe based on reports of 4,534 people who have side effects when taking Primaxin from the FDA, and is updated regularly.

What is Primaxin?

Primaxin has active ingredients of cilastatin sodium; imipenem. eHealthMe is studying from 4,540 Primaxin users. Check the latest studies of Primaxin.

What is Liver function test abnormal?

Liver function test abnormal is found to be associated with 1,493 drugs and 1,963 conditions by eHealthMe. Check the latest studies of Liver function test abnormal.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

4,534 people reported to have side effects when taking Primaxin.
Among them, 18 people (0.4%) have Liver function test abnormal.

Could Primaxin cause Liver function test abnormal?

Among these 18 people:

How long have people been on Primaxin when they have Liver function test abnormal? *

What is the gender of people who have Liver function test abnormal when taking Primaxin? *

female: 50 %
male: 50 %

What is the age of people who have Liver function test abnormal when taking Primaxin? *

What are other drugs people take besides Primaxin? *

What are other side effects people have besides Liver function test abnormal? *

Blood Alkaline Phosphatase Increased: 5 people, 27.78%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 22.22%
Fever: 4 people, 22.22%
Thrombocytopenia (decrease of platelets in blood): 4 people, 22.22%
Gamma-Glutamyltransferase Increased: 4 people, 22.22%
Septic Shock (shock due to blood infection): 4 people, 22.22%
Respiratory Syncytial Virus Infection (viral disease of respiratory system): 3 people, 16.67%
Gallstones (stone formation by bile component): 3 people, 16.67%
Embolic Stroke (stroke due to obstruction due to an embolus): 3 people, 16.67%
Cerebral Infarction (less blood supply to brain resulting tissue damage): 3 people, 16.67%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 3 people, 16.67%
Cholecystitis (infection of gallbladder): 3 people, 16.67%
Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 11.11%
Pneumonia: 2 people, 11.11%
Urinary Tract Infection: 1 person, 5.56%
High Blood Cholesterol: 1 person, 5.56%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 5.56%
Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 5.56%
Anaplastic Astrocytoma (tumour of the glial (supportive) tissue of the brain): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Primaxin and have Liver function test abnormal?

- Check whether Liver function test abnormal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Primaxin:

Primaxin (4,540 reports)

Browse all side effects of Primaxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Liver function test abnormal:

Liver function test abnormal (1,493 drugs)

Browse all the conditions that are associated with Liver function test abnormal:

Liver function test abnormal (1,963 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cilastatin sodium; imipenem (the active ingredients of Primaxin) and Primaxin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.