Prinzide and Anaphylaxis - a phase IV clinical study of FDA data

Summary:

Anaphylaxis is reported as a side effect among people who take Prinzide (hydrochlorothiazide; lisinopril), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Lipitor, and have Anaemia of malignant disease.

The phase IV clinical study analyzes which people have Anaphylaxis when taking Prinzide. It is created by eHealthMe based on reports of 2,155 people who have side effects when taking Prinzide from the FDA, and is updated regularly.

What is Prinzide?

Prinzide has active ingredients of hydrochlorothiazide; lisinopril. It is often used in high blood pressure. eHealthMe is studying from 2,218 Prinzide users. Check the latest studies of Prinzide.

What is Anaphylaxis?

Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death) is found to be associated with 1,941 drugs and 2,856 conditions by eHealthMe. Check the latest studies of Anaphylaxis.

On Jul, 17, 2026

2,155 people reported to have side effects when taking Prinzide.
Among them, 13 people (0.6%) have Anaphylaxis.

Among these 13 people:

How long have people been on Prinzide when they have Anaphylaxis? *

What is the gender of people who have Anaphylaxis when taking Prinzide? *

female: 76.92 %
male: 23.08 %

What is the age of people who have Anaphylaxis when taking Prinzide? *

What are other drugs people take besides Prinzide? *

What are other side effects people have besides Anaphylaxis? *

Dyspnea (difficult or laboured breathing): 4 people, 30.77%
Nervousness: 2 people, 15.38%
Tonsillar Hypertrophy (enlargement of the tonsils): 2 people, 15.38%
Agitation (state of anxiety or nervous excitement): 2 people, 15.38%
Swallowing Difficulty: 2 people, 15.38%
Skin Blushing/flushing (a sudden reddening of the face, neck): 2 people, 15.38%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 2 people, 15.38%
White Blood Cell Count Increased: 1 person, 7.69%
Haematocrit Abnormal: 1 person, 7.69%
Dyskinesia (abnormality or impairment of voluntary movement): 1 person, 7.69%

What are the existing conditions these people have? *

Anaemia Of Malignant Disease: 2 people, 15.38%
Hidradenitis (chronic disease of a type of sweat gland): 1 person, 7.69%
Diabetes: 1 person, 7.69%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Prinzide and have Anaphylaxis?

- Check whether Anaphylaxis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prinzide:

Prinzide (2,218 reports)

Anaphylaxis treatments and more:

Anaphylaxis (91,195 reports)

How severe was Anaphylaxis and when was it recovered:

Anaphylaxis in Prinzide

Expand to all the drugs that have ingredients of hydrochlorothiazide; lisinopril:

Anaphylaxis and drugs with ingredients of hydrochlorothiazide; lisinopril

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prinzide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Anaphylaxis:

Anaphylaxis (1,941 drugs)

Browse all the conditions that are associated with Anaphylaxis:

Anaphylaxis (2,856 conditions)

Related publications that referenced our studies

An?eli? N, Erdeljan S, Popovi? R, Bo?i? T, "Anaphylaxis on graft reperfusion during orthotopic liver transplantation: A case study", Srpski arhiv za celokupno lekarstvo, 2016 Jan .
Thangakunam B, Christopher DJ, Mathews V, Srivastava A, "Mesenchymal stromal stem cell therapy in advanced interstitial lung disease-Anaphylaxis and short-term follow-up", Lung India: official organ of Indian Chest Society, 2015 Jan .
Guensley Delva, M. D., & Muse, I, "Rare case of laryngeal edema and anaphylaxis to Ofirmev (IV Acetaminophen): Case Report", , 2012 Jan .
Azkur D, Yoldas T, Toyran M, Kocabas CN, "A pediatric case of anaphylaxis due to octreotide", Asian Pacific journal of allergy and immunology, 2011 Dec .
An?eli? N, Erdeljan S, Popovi? R, Bo?i? T, "Anaphylaxis on graft reperfusion during orthotopic liver transplantation: A case study", Srpski arhiv za celokupno lekarstvo, 2016 Jan .
Thangakunam B, Christopher DJ, Mathews V, Srivastava A, "Mesenchymal stromal stem cell therapy in advanced interstitial lung disease-Anaphylaxis and short-term follow-up", Lung India: official organ of Indian Chest Society, 2015 Jan .
Guensley Delva, M. D., & Muse, I, "Rare case of laryngeal edema and anaphylaxis to Ofirmev (IV Acetaminophen): Case Report", , 2012 Jan .
Azkur D, Yoldas T, Toyran M, Kocabas CN, "A pediatric case of anaphylaxis due to octreotide", Asian Pacific journal of allergy and immunology, 2011 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; lisinopril (the active ingredients of Prinzide) and Prinzide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.