Probiotics and Eye pain - a phase IV clinical study of FDA data


Eye pain is found among people who take Probiotics, especially for people who are female, 60+ old.

The phase IV clinical study analyzes which people take Probiotics and have Eye pain. It is created by eHealthMe based on reports of 4,197 people who have side effects when taking Probiotics from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On Jun, 30, 2022

4,197 people reported to have side effects when taking Probiotics.
Among them, 42 people (1.0%) have Eye pain.

What is Probiotics?

Probiotics has active ingredients of bifidobacteria. It is often used in irritable bowel syndrome. eHealthMe is studying from 4,582 Probiotics users for its effectiveness, alternative drugs and more.

What is Eye pain?

Eye pain is found to be associated with 2,902 drugs and 2,239 conditions by eHealthMe.

Number of Probiotics and Eye pain reports submitted per year:

Could Probiotics cause Eye pain?

Gender of people who have Eye pain when taking Probiotics *:

  • female: 89.19 %
  • male: 10.81 %

Age of people who have Eye pain when taking Probiotics *:

  • 0-1: 3.45 %
  • 2-9: 0.0 %
  • 10-19: 3.45 %
  • 20-29: 3.45 %
  • 30-39: 17.24 %
  • 40-49: 10.34 %
  • 50-59: 20.69 %
  • 60+: 41.38 %

Common drugs people take besides Probiotics *:

  1. Vitamin D: 11 people, 26.19%
  2. Restasis: 8 people, 19.05%
  3. Vitamin C: 8 people, 19.05%
  4. Vitamin D3: 7 people, 16.67%
  5. Fish Oil: 6 people, 14.29%
  6. Magnesium: 6 people, 14.29%
  7. Humira: 5 people, 11.90%
  8. Inflectra: 5 people, 11.90%
  9. Calcium: 4 people, 9.52%
  10. Omega 3: 4 people, 9.52%

Common side effects people have besides Eye pain *:

  1. Fatigue (feeling of tiredness): 16 people, 38.10%
  2. Pain In Extremity: 10 people, 23.81%
  3. Diarrhea: 9 people, 21.43%
  4. Nausea (feeling of having an urge to vomit): 9 people, 21.43%
  5. Headache (pain in head): 9 people, 21.43%
  6. Rashes (redness): 8 people, 19.05%
  7. Fever: 8 people, 19.05%
  8. Joint Pain: 8 people, 19.05%
  9. Dizziness: 7 people, 16.67%
  10. Pain: 7 people, 16.67%

Common conditions people have *:

  1. Dry Eyes (lack of adequate tears): 9 people, 21.43%
  2. Pain: 5 people, 11.90%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 9.52%
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 7.14%
  5. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 7.14%
  6. High Blood Cholesterol: 3 people, 7.14%
  7. High Blood Pressure: 3 people, 7.14%
  8. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 4.76%
  9. Cardiac Disorder: 2 people, 4.76%
  10. Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 2 people, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Probiotics and have Eye pain?

Check whether Eye pain is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of Probiotics:

Eye pain treatments and more:

COVID vaccines that are related to Eye pain:

How severe was Eye pain and when was it recovered:

Expand to all the drugs that have ingredients of bifidobacteria:

Common drugs associated with Eye pain:

All the drugs that are associated with Eye pain:

Common conditions associated with Eye pain:

All the conditions that are associated with Eye pain:

How the study uses the data?

The study uses data from the FDA. It is based on bifidobacteria (the active ingredients of Probiotics) and Probiotics (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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