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Profen and Enterococcal infection - a phase IV clinical study of FDA data

Summary:

Enterococcal infection is reported as a side effect among people who take Profen (ibuprofen), especially for people who are male, 40-49 old, have been taking the drug for < 1 month also take Acetaminophen, and have Joint pain.

The phase IV clinical study analyzes which people have Enterococcal infection when taking Profen. It is created by eHealthMe based on reports of 239,319 people who have side effects when taking Profen from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

What is Enterococcal infection?

Enterococcal infection is found to be associated with 624 drugs and 760 conditions by eHealthMe. Check the latest studies of Enterococcal infection.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

239,319 people reported to have side effects when taking Profen.
Among them, 68 people (0.03%) have Enterococcal infection.

Could Profen cause Enterococcal infection?

Among these 68 people:

How long have people been on Profen when they have Enterococcal infection? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Enterococcal infection when taking Profen? *

  • female: 36.92 %
  • male: 63.08 %

What is the age of people who have Enterococcal infection when taking Profen? *

  • 0-1: 5.0 %
  • 2-9: 6.67 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 6.67 %
  • 40-49: 33.33 %
  • 50-59: 23.33 %
  • 60+: 25.0 %

What are other drugs people take besides Profen? *

  1. Acetaminophen: 12 people, 17.65%
  2. Clarithromycin: 9 people, 13.24%
  3. Nystatin: 9 people, 13.24%
  4. Amoxicillin: 9 people, 13.24%
  5. Lorazepam: 8 people, 11.76%
  6. Gabapentin: 7 people, 10.29%
  7. Famotidine: 7 people, 10.29%
  8. Imatinib Mesylate: 7 people, 10.29%
  9. Celexa: 6 people, 8.82%
  10. Cerebyx: 6 people, 8.82%

What are other side effects people have besides Enterococcal infection? *

  1. Acute Kidney Failure: 23 people, 33.82%
  2. Dehydration (dryness resulting from the removal of water): 22 people, 32.35%
  3. Staphylococcal Infection (an infection with staphylococcus bacteria): 22 people, 32.35%
  4. Rashes (redness): 20 people, 29.41%
  5. Fever: 19 people, 27.94%
  6. Itching: 18 people, 26.47%
  7. Swallowing Difficulty: 16 people, 23.53%
  8. Urinary Tract Infection: 14 people, 20.59%
  9. Skin Exfoliation (removal of the oldest dead skin cells): 14 people, 20.59%
  10. Skin Hyperpigmentation (disorders affect the colour of your skin): 13 people, 19.12%

What are the existing conditions these people have? *

  1. Joint Pain: 13 people, 19.12%
  2. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 12 people, 17.65%
  3. High Blood Pressure: 9 people, 13.24%
  4. Respiratory Tract Infection: 9 people, 13.24%
  5. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 7 people, 10.29%
  6. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 6 people, 8.82%
  7. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 7.35%
  8. Erythema Multiforme (a type of hypersensitivity reaction): 5 people, 7.35%
  9. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 7.35%
  10. Fever: 4 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Profen and have Enterococcal infection?

- Check whether Enterococcal infection is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Profen:

Enterococcal infection treatments and more:

How severe was Enterococcal infection and when was it recovered:

Expand to all the drugs that have ingredients of ibuprofen:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Profen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Enterococcal infection:

Browse all the conditions that are associated with Enterococcal infection:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Profen) and Profen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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