Profen and Erythrodermic psoriasis - a phase IV clinical study of FDA data

Summary:

Erythrodermic psoriasis is reported as a side effect among people who take Profen (ibuprofen), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Co-Codamol, and have Depressed mood.

The phase IV clinical study analyzes which people have Erythrodermic psoriasis when taking Profen. It is created by eHealthMe based on reports of 239,319 people who have side effects when taking Profen from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

What is Erythrodermic psoriasis?

Erythrodermic psoriasis (generalized redness of the skin) is found to be associated with 77 drugs and 176 conditions by eHealthMe. Check the latest studies of Erythrodermic psoriasis.



On Jul, 14, 2026

239,319 people reported to have side effects when taking Profen.
Among them, 18 people (0.01%) have Erythrodermic psoriasis.

Could Profen cause Erythrodermic psoriasis?

Among these 18 people:

How long have people been on Profen when they have Erythrodermic psoriasis? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Erythrodermic psoriasis when taking Profen? *

  • female: 29.41 %
  • male: 70.59 %

What is the age of people who have Erythrodermic psoriasis when taking Profen? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 6.67 %
  • 30-39: 6.67 %
  • 40-49: 40.0 %
  • 50-59: 6.67 %
  • 60+: 40.0 %

What are other drugs people take besides Profen? *

  1. Co-Codamol: 5 people, 27.78%
  2. Effexor: 4 people, 22.22%
  3. Methotrexate: 3 people, 16.67%
  4. Venlafaxine Hydrochloride: 2 people, 11.11%
  5. Clonazepam: 2 people, 11.11%
  6. Zolpidem: 1 person, 5.56%
  7. Halobetasol Propionate: 1 person, 5.56%
  8. Ginkgo: 1 person, 5.56%
  9. Gabapentin: 1 person, 5.56%
  10. Folic Acid: 1 person, 5.56%

What are other side effects people have besides Erythrodermic psoriasis? *

  1. Photosensitivity Reaction: 9 people, 50.00%
  2. Stress And Anxiety: 2 people, 11.11%
  3. Cough: 2 people, 11.11%
  4. Drug Ineffective: 2 people, 11.11%
  5. Rashes (redness): 2 people, 11.11%
  6. Psoriasis (immune-mediated disease that affects the skin): 2 people, 11.11%
  7. Wheezing (a high-pitched whistling sound made while you breath): 1 person, 5.56%
  8. Dyspnea (difficult or laboured breathing): 1 person, 5.56%
  9. Hyperhidrosis (abnormally increased sweating): 1 person, 5.56%
  10. High Blood Cholesterol: 1 person, 5.56%

What are the existing conditions these people have? *

  1. Depressed Mood: 8 people, 44.44%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 16.67%
  3. Psoriasis (immune-mediated disease that affects the skin): 1 person, 5.56%
  4. High Blood Pressure: 1 person, 5.56%
  5. High Blood Cholesterol: 1 person, 5.56%
  6. Gout (uric acid crystals building up in the body): 1 person, 5.56%
  7. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 5.56%
  8. Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Profen and have Erythrodermic psoriasis?

- Check whether Erythrodermic psoriasis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Profen:

Erythrodermic psoriasis treatments and more:

How severe was Erythrodermic psoriasis and when was it recovered:

Expand to all the drugs that have ingredients of ibuprofen:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Profen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Erythrodermic psoriasis:

Browse all the conditions that are associated with Erythrodermic psoriasis:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Profen) and Profen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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