Profen and Glomerulonephritis rapidly progressive - a phase IV clinical study of FDA data

Summary:

Glomerulonephritis rapidly progressive is reported as a side effect among people who take Profen (ibuprofen), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Pantoprazole, and have High blood pressure.

The phase IV clinical study analyzes which people have Glomerulonephritis rapidly progressive when taking Profen. It is created by eHealthMe based on reports of 239,319 people who have side effects when taking Profen from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,312 Profen users. Check the latest studies of Profen.

What is Glomerulonephritis rapidly progressive?

Glomerulonephritis rapidly progressive (a syndrome of the kidney that is characterized by a rapid loss of renal function) is found to be associated with 88 drugs and 203 conditions by eHealthMe. Check the latest studies of Glomerulonephritis rapidly progressive.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

239,319 people reported to have side effects when taking Profen.
Among them, 19 people (0.01%) have Glomerulonephritis rapidly progressive.

Could Profen cause Glomerulonephritis rapidly progressive?

Among these 19 people:

How long have people been on Profen when they have Glomerulonephritis rapidly progressive? *

  • < 1 month: 33.33 %
  • 1 - 6 months: 66.67 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Glomerulonephritis rapidly progressive when taking Profen? *

  • female: 58.82 %
  • male: 41.18 %

What is the age of people who have Glomerulonephritis rapidly progressive when taking Profen? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 11.76 %
  • 30-39: 0.0 %
  • 40-49: 29.41 %
  • 50-59: 5.88 %
  • 60+: 52.94 %

What are other drugs people take besides Profen? *

  1. Amlodipine: 6 people, 31.58%
  2. Pantoprazole: 6 people, 31.58%
  3. Zolpidem: 5 people, 26.32%
  4. Novolin 70/30: 2 people, 10.53%
  5. Amoxil: 2 people, 10.53%
  6. Avelox: 2 people, 10.53%
  7. Cefazolin: 2 people, 10.53%
  8. Escitalopram: 2 people, 10.53%
  9. Farxiga: 2 people, 10.53%
  10. Humalog Pen: 2 people, 10.53%

What are other side effects people have besides Glomerulonephritis rapidly progressive? *

  1. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 5 people, 26.32%
  2. Acute Kidney Failure: 4 people, 21.05%
  3. Goodpasture Syndrome (immune system mistakenly attacks and destroys healthy body tissue): 4 people, 21.05%
  4. Interstitial Nephritis (inflammation of the kidney): 3 people, 15.79%
  5. Renal Injury (kidney injury): 3 people, 15.79%
  6. Microscopic Polyangiitis (inflammation involving multiple blood or lymph small-vessel): 2 people, 10.53%
  7. Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 2 people, 10.53%
  8. Diabetic Nephropathy (diabetic kidney disease): 2 people, 10.53%
  9. Nephrogenic Anaemia (anaemia due to kidney disease): 2 people, 10.53%
  10. Nausea (feeling of having an urge to vomit): 2 people, 10.53%

What are the existing conditions these people have? *

  1. High Blood Pressure: 6 people, 31.58%
  2. Nausea (feeling of having an urge to vomit): 3 people, 15.79%
  3. Nasopharyngitis (inflammation of the nasopharynx): 3 people, 15.79%
  4. Weight Loss: 2 people, 10.53%
  5. Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 2 people, 10.53%
  6. Cough: 2 people, 10.53%
  7. Depression: 2 people, 10.53%
  8. Diabetes: 2 people, 10.53%
  9. Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 2 people, 10.53%
  10. Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Profen and have Glomerulonephritis rapidly progressive?

- Check whether Glomerulonephritis rapidly progressive is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Profen:

Glomerulonephritis rapidly progressive treatments and more:

How severe was Glomerulonephritis rapidly progressive and when was it recovered:

Expand to all the drugs that have ingredients of ibuprofen:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Profen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Glomerulonephritis rapidly progressive:

Browse all the conditions that are associated with Glomerulonephritis rapidly progressive:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Profen) and Profen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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