Profen and Itching - a phase IV clinical study of FDA data

Summary:

Itching is reported as a side effect among people who take Profen (ibuprofen), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Enbrel, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Itching when taking Profen. It is created by eHealthMe based on reports of 239,319 people who have side effects when taking Profen from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,297 Profen users. Check the latest studies of Profen.

What is Itching?

Itching is found to be associated with 3,241 drugs and 4,479 conditions by eHealthMe. Check the latest studies of Itching.

On Jul, 30, 2025

239,319 people reported to have side effects when taking Profen.
Among them, 9,169 people (3.83%) have Itching.

Among these 9,169 people:

How long have people been on Profen when they have Itching? *

What is the gender of people who have Itching when taking Profen? *

female: 79.56 %
male: 20.44 %

What is the age of people who have Itching when taking Profen? *

What are other drugs people take besides Profen? *

What are other side effects people have besides Itching? *

Rashes (redness): 4,999 people, 54.52%
Fatigue (feeling of tiredness): 3,599 people, 39.25%
Peripheral Swelling: 3,361 people, 36.66%
Joint Swelling: 3,276 people, 35.73%
Dyspnea (difficult or laboured breathing): 3,189 people, 34.78%
Sinusitis (inflammation of sinus): 3,165 people, 34.52%
Lower Respiratory Tract Infection: 3,165 people, 34.52%
Joint Pain: 3,146 people, 34.31%
Fever: 2,952 people, 32.20%
Hypersensitivity: 2,842 people, 31.00%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3,490 people, 38.06%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 783 people, 8.54%
Psoriasis (immune-mediated disease that affects the skin): 559 people, 6.10%
High Blood Pressure: 342 people, 3.73%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 309 people, 3.37%
Stress And Anxiety: 298 people, 3.25%
Fever: 263 people, 2.87%
Headache (pain in head): 247 people, 2.69%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 247 people, 2.69%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 234 people, 2.55%

* Approximation only. Some reports may have incomplete information.

Do you take Profen and have Itching?

- Check whether Itching is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Profen:

Profen (245,297 reports)

Itching treatments and more:

Itching (398,789 reports)

How severe was Itching and when was it recovered:

Itching in Profen

Browse all side effects of Profen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Itching:

Itching (3,241 drugs)

Browse all the conditions that are associated with Itching:

Itching (4,479 conditions)

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Profen) and Profen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.