Profen and Jitters - a phase IV clinical study of FDA data

Summary:

Jitters is reported as a side effect among people who take Profen (ibuprofen), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Acetaminophen, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Jitters when taking Profen. It is created by eHealthMe based on reports of 239,319 people who have side effects when taking Profen from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,301 Profen users. Check the latest studies of Profen.

What is Jitters?

Jitters (to make someone nervous or frightened) is found to be associated with 4,463 drugs and 5,415 conditions by eHealthMe. Check the latest studies of Jitters.

On Nov, 17, 2025

239,319 people reported to have side effects when taking Profen.
Among them, 10,626 people (4.44%) have Jitters.

Among these 10,626 people:

How long have people been on Profen when they have Jitters? *

What is the gender of people who have Jitters when taking Profen? *

female: 70.32 %
male: 29.68 %

What is the age of people who have Jitters when taking Profen? *

What are other drugs people take besides Profen? *

What are other side effects people have besides Jitters? *

Depression: 3,087 people, 29.05%
Fatigue (feeling of tiredness): 2,619 people, 24.65%
Emotional Distress: 2,536 people, 23.87%
Injury: 2,171 people, 20.43%
Headache (pain in head): 2,129 people, 20.04%
Nausea (feeling of having an urge to vomit): 2,075 people, 19.53%
Dizziness: 1,890 people, 17.79%
Dyspnea (difficult or laboured breathing): 1,847 people, 17.38%
Joint Pain: 1,813 people, 17.06%
Weakness: 1,810 people, 17.03%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 953 people, 8.97%
Hiv Infection: 879 people, 8.27%
Depression: 874 people, 8.23%
Birth Control: 813 people, 7.65%
High Blood Pressure: 736 people, 6.93%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 721 people, 6.79%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 623 people, 5.86%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 462 people, 4.35%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 454 people, 4.27%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 450 people, 4.23%

* Approximation only. Some reports may have incomplete information.

Do you take Profen and have Jitters?

- Check whether Jitters is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Profen:

Profen (245,301 reports)

Jitters treatments and more:

Jitters (637,366 reports)

Common Profen side effects:

Browse all side effects of Profen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Jitters:

Browse all the drugs that are associated with Jitters:

Jitters (4,463 drugs)

Common conditions associated with Jitters:

Ms: 25,919 reports
Depression: 24,778 reports
Antidepressant therapy: 24,777 reports
Hiv infection: 17,583 reports
Pain: 17,347 reports
Pain relief: 17,163 reports
Anxiety: 16,842 reports
Stress: 16,840 reports
Anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension: 16,039 reports
Rheumatoid arthritis aggravated: 15,867 reports

Browse all the conditions that are associated with Jitters:

Jitters (5,415 conditions)

Drugs similar to Profen and Jitters :

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Profen) and Profen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.