Profen and Left ventricle outflow tract obstruction - a phase IV clinical study of FDA data

Summary:

Left ventricle outflow tract obstruction is reported as a side effect among people who take Profen (ibuprofen), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Effexor Xr, and have Depression.

The phase IV clinical study analyzes which people have Left ventricle outflow tract obstruction when taking Profen. It is created by eHealthMe based on reports of 239,319 people who have side effects when taking Profen from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,312 Profen users. Check the latest studies of Profen.

What is Left ventricle outflow tract obstruction?

Left ventricle outflow tract obstruction is found to be associated with 39 drugs and 133 conditions by eHealthMe. Check the latest studies of Left ventricle outflow tract obstruction.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

239,319 people reported to have side effects when taking Profen.
Among them, 15 people (0.01%) have Left ventricle outflow tract obstruction.

Could Profen cause Left ventricle outflow tract obstruction?

Among these 15 people:

How long have people been on Profen when they have Left ventricle outflow tract obstruction? *

What is the gender of people who have Left ventricle outflow tract obstruction when taking Profen? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Left ventricle outflow tract obstruction when taking Profen? *

What are other drugs people take besides Profen? *

Macrobid: 10 people, 66.67%
Flonase: 10 people, 66.67%
Sulfamethoxazole And Trimethoprim: 10 people, 66.67%
Paxil Cr: 10 people, 66.67%
Ambien: 10 people, 66.67%
Cephalexin: 10 people, 66.67%
Effexor Xr: 10 people, 66.67%
Benadryl: 6 people, 40.00%
Motrin: 6 people, 40.00%
Hydrocortisone: 6 people, 40.00%

What are other side effects people have besides Left ventricle outflow tract obstruction? *

Injury: 10 people, 66.67%
Sinus Arrhythmia (a naturally occurring variation in heart rate that occurs during a breathing cycle): 10 people, 66.67%
Heart Valve Stenosis (abnormal narrowing of the aortic valve in the heart): 10 people, 66.67%
Left Ventricular Hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart): 10 people, 66.67%
Lung Disorder (lung disease): 10 people, 66.67%
Emotional Disorder: 10 people, 66.67%
Drug Exposure During Pregnancy: 10 people, 66.67%
Developmental Delay: 10 people, 66.67%
Persistent Foetal Circulation (baby's blood does not need to pass by the lungs): 10 people, 66.67%
Coarctation Of The Aorta (narrowing of the part of aorta): 10 people, 66.67%

What are the existing conditions these people have? *

Depression: 6 people, 40.00%
Malignant Melanoma (skin cancer rises from melancytes): 5 people, 33.33%
High Blood Pressure: 3 people, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Profen and have Left ventricle outflow tract obstruction?

- Check whether Left ventricle outflow tract obstruction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Profen:

Profen (245,312 reports)

Left ventricle outflow tract obstruction treatments and more:

Left ventricle outflow tract obstruction (444 reports)

How severe was Left ventricle outflow tract obstruction and when was it recovered:

Left ventricle outflow tract obstruction in Profen

Expand to all the drugs that have ingredients of ibuprofen:

Left ventricle outflow tract obstruction and drugs with ingredients of ibuprofen (16 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Profen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Left ventricle outflow tract obstruction:

Left ventricle outflow tract obstruction (39 drugs)

Browse all the conditions that are associated with Left ventricle outflow tract obstruction:

Left ventricle outflow tract obstruction (133 conditions)

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Profen) and Profen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.