Profen and Nail abnormalities - a phase IV clinical study of FDA data

Summary:

Nail abnormalities is reported as a side effect among people who take Profen (ibuprofen), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Naproxen, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Nail abnormalities when taking Profen. It is created by eHealthMe based on reports of 239,319 people who have side effects when taking Profen from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,298 Profen users. Check the latest studies of Profen.

What is Nail abnormalities?

Nail abnormalities (abnormal nail) is found to be associated with 242 drugs and 636 conditions by eHealthMe. Check the latest studies of Nail abnormalities.

On Oct, 07, 2025

239,319 people reported to have side effects when taking Profen.
Among them, 29 people (0.01%) have Nail abnormalities.

Among these 29 people:

How long have people been on Profen when they have Nail abnormalities? *

What is the gender of people who have Nail abnormalities when taking Profen? *

female: 68.97 %
male: 31.03 %

What is the age of people who have Nail abnormalities when taking Profen? *

What are other drugs people take besides Profen? *

What are other side effects people have besides Nail abnormalities? *

Rashes (redness): 16 people, 55.17%
Pain In Extremity: 15 people, 51.72%
Joint Pain: 12 people, 41.38%
Arthropathy: 9 people, 31.03%
Hypoaesthesia (reduced sense of touch or sensation): 9 people, 31.03%
Drug Ineffective: 8 people, 27.59%
Nasopharyngitis (inflammation of the nasopharynx): 7 people, 24.14%
Nausea (feeling of having an urge to vomit): 7 people, 24.14%
Weakness: 7 people, 24.14%
Fungal Nail Infection: 7 people, 24.14%

What are the existing conditions these people have? *

Stress And Anxiety: 5 people, 17.24%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 17.24%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 13.79%
Breast Cancer Metastatic: 4 people, 13.79%
Breast Cancer: 3 people, 10.34%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 6.90%
Gastric Disorder (disease of stomach): 2 people, 6.90%
White Blood Cell Count Decreased: 1 person, 3.45%
Gastric Ulcer (stomach ulcer): 1 person, 3.45%
Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Profen and have Nail abnormalities?

- Check whether Nail abnormalities is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Profen:

Profen (245,298 reports)

Browse all side effects of Profen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nail abnormalities:

Nail abnormalities (242 drugs)

Browse all the conditions that are associated with Nail abnormalities:

Nail abnormalities (636 conditions)

Drugs similar to Profen and Nail abnormalities :

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Profen) and Profen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.