Profen and Overactive bladder - a phase IV clinical study of FDA data

Summary:

Overactive bladder is reported as a side effect among people who take Profen (ibuprofen), especially for people who are 60+ old, have been taking the drug for 6 - 12 months also take Celecoxib, and have Relapsing-remitting multiple sclerosis.

The phase IV clinical study analyzes which people have Overactive bladder when taking Profen. It is created by eHealthMe based on reports of 239,319 people who have side effects when taking Profen from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,299 Profen users. Check the latest studies of Profen.

What is Overactive bladder?

Overactive bladder (a condition in which the bladder squeezes urine out at the wrong time) is found to be associated with 437 drugs and 599 conditions by eHealthMe. Check the latest studies of Overactive bladder.

On Oct, 16, 2025

239,319 people reported to have side effects when taking Profen.
Among them, 44 people (0.02%) have Overactive bladder.

Among these 44 people:

How long have people been on Profen when they have Overactive bladder? *

What is the age of people who have Overactive bladder when taking Profen? *

What are other drugs people take besides Profen? *

What are other side effects people have besides Overactive bladder? *

Joint Pain: 25 people, 56.82%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 20 people, 45.45%
Insomnia (sleeplessness): 18 people, 40.91%
Spinal Osteoarthritis (joint cartilage loss in spine): 17 people, 38.64%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 17 people, 38.64%
Fall: 17 people, 38.64%
Fatigue (feeling of tiredness): 17 people, 38.64%
Pain In Extremity: 16 people, 36.36%
Depression: 16 people, 36.36%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 16 people, 36.36%

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 10 people, 22.73%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 9 people, 20.45%
Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 9 people, 20.45%
Joint Pain: 4 people, 9.09%
Multiple Myeloma (cancer of the plasma cells): 4 people, 9.09%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 6.82%
Breast Cancer: 3 people, 6.82%
Osteopenia (a condition where bone mineral density is lower than normal): 3 people, 6.82%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 2 people, 4.55%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Profen and have Overactive bladder?

- Check whether Overactive bladder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Profen:

Profen (245,299 reports)

Browse all side effects of Profen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Overactive bladder:

Overactive bladder (437 drugs)

Browse all the conditions that are associated with Overactive bladder:

Overactive bladder (599 conditions)

Drugs similar to Profen and Overactive bladder :

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Profen) and Profen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.