Profen and Thyroidectomy - a phase IV clinical study of FDA data

Summary:

Thyroidectomy is reported as a side effect among people who take Profen (ibuprofen), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Xyrem, and have Narcolepsy.

The phase IV clinical study analyzes which people have Thyroidectomy when taking Profen. It is created by eHealthMe based on reports of 239,319 people who have side effects when taking Profen from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,305 Profen users. Check the latest studies of Profen.

What is Thyroidectomy?

Thyroidectomy is found to be associated with 585 drugs and 499 conditions by eHealthMe. Check the latest studies of Thyroidectomy.

On Jan, 14, 2026

239,319 people reported to have side effects when taking Profen.
Among them, 26 people (0.01%) have Thyroidectomy.

Among these 26 people:

How long have people been on Profen when they have Thyroidectomy? *

What is the gender of people who have Thyroidectomy when taking Profen? *

female: 64 %
male: 36 %

What is the age of people who have Thyroidectomy when taking Profen? *

What are other drugs people take besides Profen? *

Xyrem: 8 people, 30.77%
Synthroid: 5 people, 19.23%
Vitamin D3: 5 people, 19.23%
Norco: 5 people, 19.23%
Vimovo: 4 people, 15.38%
Aspirin: 4 people, 15.38%
Oxycodone And Acetaminophen: 4 people, 15.38%
Zyrtec: 4 people, 15.38%
Welchol: 4 people, 15.38%
Lysine: 3 people, 11.54%

What are other side effects people have besides Thyroidectomy? *

Drug Ineffective: 4 people, 15.38%
Cough: 4 people, 15.38%
Stress And Anxiety: 3 people, 11.54%
Muscle Spasms (muscle contraction): 3 people, 11.54%
Lung Neoplasm Malignant (cancer tumour of lung): 3 people, 11.54%
Dehydration (dryness resulting from the removal of water): 2 people, 7.69%
Cancer - Throat Or Larynx: 2 people, 7.69%
Mobility Decreased (ability to move is reduced): 2 people, 7.69%
Constipation: 2 people, 7.69%
Lymphoedema (localized fluid retention and tissue swelling): 2 people, 7.69%

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 30.77%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 30.77%
Headache (pain in head): 3 people, 11.54%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 7.69%
Osteoporosis (bones weak and more likely to break): 2 people, 7.69%
Diabetes: 2 people, 7.69%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 7.69%
High Blood Pressure: 1 person, 3.85%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 1 person, 3.85%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Profen and have Thyroidectomy?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Profen:

Profen (245,305 reports)

Thyroidectomy treatments and more:

Thyroidectomy (8,953 reports)

Browse all side effects of Profen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thyroidectomy:

Thyroidectomy (585 drugs)

Browse all the conditions that are associated with Thyroidectomy:

Thyroidectomy (499 conditions)

Drugs similar to Profen and Thyroidectomy :

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Profen) and Profen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.