Profen and Thyroiditis - a phase IV clinical study of FDA data

Summary:

Thyroiditis is reported as a side effect among people who take Profen (ibuprofen), especially for people who are female, 40-49 old, also take Albuterol, and have Eczema.

The phase IV clinical study analyzes which people have Thyroiditis when taking Profen. It is created by eHealthMe based on reports of 239,319 people who have side effects when taking Profen from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,307 Profen users. Check the latest studies of Profen.

What is Thyroiditis?

Thyroiditis (inflammation of thyroid gland) is found to be associated with 338 drugs and 389 conditions by eHealthMe. Check the latest studies of Thyroiditis.



On Nov, 23, 2025

239,319 people reported to have side effects when taking Profen.
Among them, 45 people (0.02%) have Thyroiditis.

Could Profen cause Thyroiditis?

Among these 45 people:

What is the gender of people who have Thyroiditis when taking Profen? *

  • female: 57.78 %
  • male: 42.22 %

What is the age of people who have Thyroiditis when taking Profen? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 28.21 %
  • 30-39: 10.26 %
  • 40-49: 30.77 %
  • 50-59: 12.82 %
  • 60+: 17.95 %

What are other drugs people take besides Profen? *

  1. Albuterol: 17 people, 37.78%
  2. Flexeril: 12 people, 26.67%
  3. Vicodin: 11 people, 24.44%
  4. Zofran: 11 people, 24.44%
  5. Colace: 11 people, 24.44%
  6. Valtrex: 11 people, 24.44%
  7. Femara: 10 people, 22.22%
  8. Zantac: 10 people, 22.22%
  9. Famotidine: 10 people, 22.22%
  10. Oxycontin: 10 people, 22.22%

What are other side effects people have besides Thyroiditis? *

  1. Dizziness: 26 people, 57.78%
  2. Fever: 22 people, 48.89%
  3. Stress And Anxiety: 20 people, 44.44%
  4. Fall: 18 people, 40.00%
  5. Fainting (loss of consciousness and postural tone): 17 people, 37.78%
  6. Pilonidal Cyst: 17 people, 37.78%
  7. Insomnia (sleeplessness): 16 people, 35.56%
  8. Headache (pain in head): 16 people, 35.56%
  9. Dyspnea (difficult or laboured breathing): 16 people, 35.56%
  10. Injury: 15 people, 33.33%

What are the existing conditions these people have? *

  1. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 9 people, 20.00%
  2. Breast Cancer Metastatic: 8 people, 17.78%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 8.89%
  4. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 8.89%
  5. Nausea (feeling of having an urge to vomit): 3 people, 6.67%
  6. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 6.67%
  7. Metastases To Bone (cancer spreads to bone): 3 people, 6.67%
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 4.44%
  9. Gastric Ph Decreased: 2 people, 4.44%
  10. Gastric Disorder (disease of stomach): 2 people, 4.44%

* Approximation only. Some reports may have incomplete information.

Do you take Profen and have Thyroiditis?

- Check whether Thyroiditis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Profen:

Thyroiditis treatments and more:

How severe was Thyroiditis and when was it recovered:

Expand to all the drugs that have ingredients of ibuprofen:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Profen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thyroiditis:

Browse all the conditions that are associated with Thyroiditis:

Drugs similar to Profen and Thyroiditis :

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Profen) and Profen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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