Prograf and Presyncope - a phase IV clinical study of FDA data
Summary:
Presyncope is reported as a side effect among people who take Prograf (tacrolimus), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Torsemide, and have High blood cholesterol.
The phase IV clinical study analyzes which people have Presyncope when taking Prograf. It is created by eHealthMe based on reports of 41,725 people who have side effects when taking Prograf from the FDA, and is updated regularly.
What is Prograf?
Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.
What is Presyncope?
Presyncope is found to be associated with 1,358 drugs and 1,286 conditions by eHealthMe. Check the latest studies of Presyncope.
41,725 people reported to have side effects when taking Prograf.
Among them, 65 people (0.16%) have Presyncope.

Among these 65 people:
How long have people been on Prograf when they have Presyncope? *
- < 1 month: 66.67 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 33.33 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Presyncope when taking Prograf? *
- female: 6.78 %
- male: 93.22 %
What is the age of people who have Presyncope when taking Prograf? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 3.39 %
- 30-39: 0.0 %
- 40-49: 5.08 %
- 50-59: 0.0 %
- 60+: 91.53 %
What are other drugs people take besides Prograf? *
- Sodium Bicarbonate: 49 people, 75.38%
- Furosemide: 49 people, 75.38%
- Carvedilol: 49 people, 75.38%
- Torsemide: 49 people, 75.38%
- Candesartan Cilexetil: 48 people, 73.85%
- Tacrolimus: 48 people, 73.85%
- Aranesp: 48 people, 73.85%
- Tamsulosin Hydrochloride: 47 people, 72.31%
- Hygroton: 47 people, 72.31%
- Myfortic: 47 people, 72.31%
What are other side effects people have besides Presyncope? *
- Dizziness: 52 people, 80.00%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 52 people, 80.00%
- Oedema Peripheral (superficial swelling): 50 people, 76.92%
- Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 50 people, 76.92%
- Bradycardia (abnormally slow heart action): 49 people, 75.38%
- Basal Cell Carcinoma (a skin cancer, it rarely metastasizes or kills): 49 people, 75.38%
- Rectal Prolapse (falling of rectum from normal place): 49 people, 75.38%
- Hepatic Steatosis (fatty liver disease): 49 people, 75.38%
- Enlarged Prostate: 49 people, 75.38%
- Hepatomegaly (abnormal enlargement of the liver): 49 people, 75.38%
What are the existing conditions these people have? *
- High Blood Cholesterol: 43 people, 66.15%
- Prostate Infection: 42 people, 64.62%
- Cardiac Disorder: 41 people, 63.08%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 41 people, 63.08%
- Abdominal Discomfort: 40 people, 61.54%
- Blood Pressure Abnormal: 37 people, 56.92%
- High Blood Pressure: 16 people, 24.62%
- Acute Graft Versus Host Disease (acute complication following an allogeneic tissue/blood transplant): 2 people, 3.08%
- Bone Marrow Conditioning Regimen: 1 person, 1.54%
- Angioimmunoblastic T-Cell Lymphoma (mature t-cell cancer of the blood or lymph vessel): 1 person, 1.54%
* Approximation only. Some reports may have incomplete information.
Do you take Prograf and have Presyncope?
- Check whether Presyncope is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Prograf:
- Prograf (42,230 reports)
Presyncope treatments and more:
- Presyncope (26,156 reports)
How severe was Presyncope and when was it recovered:
Expand to all the drugs that have ingredients of tacrolimus:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Prograf:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Presyncope:
- Presyncope (1,358 drugs)
Browse all the conditions that are associated with Presyncope:
- Presyncope (1,286 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on tacrolimus (the active ingredients of Prograf) and Prograf (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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