Prograf and Protein urine present - a phase IV clinical study of FDA data

Summary:

Protein urine present is reported as a side effect among people who take Prograf (tacrolimus), especially for people who are male, 40-49 old, have been taking the drug for 1 - 6 months also take Cellcept, and have Lupus nephritis.

The phase IV clinical study analyzes which people have Protein urine present when taking Prograf. It is created by eHealthMe based on reports of 41,725 people who have side effects when taking Prograf from the FDA, and is updated regularly.

What is Prograf?

Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.

What is Protein urine present?

Protein urine present is found to be associated with 675 drugs and 820 conditions by eHealthMe. Check the latest studies of Protein urine present.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

41,725 people reported to have side effects when taking Prograf.
Among them, 47 people (0.11%) have Protein urine present.

Could Prograf cause Protein urine present?

Among these 47 people:

How long have people been on Prograf when they have Protein urine present? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 50.0 %
  • 6 - 12 months: 12.5 %
  • 1 - 2 years: 25.0 %
  • 2 - 5 years: 12.5 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Protein urine present when taking Prograf? *

  • female: 46.51 %
  • male: 53.49 %

What is the age of people who have Protein urine present when taking Prograf? *

  • 0-1: 0.0 %
  • 2-9: 5.13 %
  • 10-19: 10.26 %
  • 20-29: 10.26 %
  • 30-39: 12.82 %
  • 40-49: 25.64 %
  • 50-59: 17.95 %
  • 60+: 17.95 %

What are other drugs people take besides Prograf? *

  1. Cellcept: 14 people, 29.79%
  2. Lipitor: 9 people, 19.15%
  3. Rapamune: 6 people, 12.77%
  4. Tegsedi: 6 people, 12.77%
  5. Prednisone: 5 people, 10.64%
  6. Sirolimus: 5 people, 10.64%
  7. Lasix: 5 people, 10.64%
  8. Prednisolone: 5 people, 10.64%
  9. Myfortic: 4 people, 8.51%
  10. Doxycycline: 4 people, 8.51%

What are other side effects people have besides Protein urine present? *

  1. Blood Creatinine Increased: 13 people, 27.66%
  2. Diarrhea: 13 people, 27.66%
  3. Blood Urea Increased: 12 people, 25.53%
  4. High Blood Pressure: 10 people, 21.28%
  5. Blood Albumin Decreased: 8 people, 17.02%
  6. Blood Lactate Dehydrogenase Increased: 7 people, 14.89%
  7. Fatigue (feeling of tiredness): 7 people, 14.89%
  8. Haemoglobin Decreased: 7 people, 14.89%
  9. Haematocrit Decreased: 7 people, 14.89%
  10. Hyperkalemia (damage to or disease of the kidney): 7 people, 14.89%

What are the existing conditions these people have? *

  1. Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 8 people, 17.02%
  2. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 7 people, 14.89%
  3. Hereditary Neuropathic Amyloidosis (hereditary- diseases resulting from abnormal deposition of certain proteins (amyloid) in various bodily areas by problems with signals from the nerves): 6 people, 12.77%
  4. Constipation: 4 people, 8.51%
  5. Osteoporosis (bones weak and more likely to break): 3 people, 6.38%
  6. Labor Induction: 3 people, 6.38%
  7. High Blood Cholesterol: 3 people, 6.38%
  8. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 6.38%
  9. Ovarian Failure (ovary is not functioning): 2 people, 4.26%
  10. Pain In Extremity: 2 people, 4.26%

* Approximation only. Some reports may have incomplete information.

Do you take Prograf and have Protein urine present?

- Check whether Protein urine present is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prograf:

Protein urine present treatments and more:

How severe was Protein urine present and when was it recovered:

Expand to all the drugs that have ingredients of tacrolimus:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prograf:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Protein urine present:

Browse all the conditions that are associated with Protein urine present:


How the study uses the data?

The study uses data from the FDA. It is based on tacrolimus (the active ingredients of Prograf) and Prograf (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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