Prograf and Ventricular tachycardia - a phase IV clinical study of FDA data
Summary:
Ventricular tachycardia is reported as a side effect among people who take Prograf (tacrolimus), especially for people who are male, 50-59 old, have been taking the drug for 1 - 6 months also take Prednisone, and have Herpes zoster.
The phase IV clinical study analyzes which people have Ventricular tachycardia when taking Prograf. It is created by eHealthMe based on reports of 41,725 people who have side effects when taking Prograf from the FDA, and is updated regularly.
What is Prograf?
Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.
What is Ventricular tachycardia?
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart) is found to be associated with 1,281 drugs and 2,098 conditions by eHealthMe. Check the latest studies of Ventricular tachycardia.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
41,725 people reported to have side effects when taking Prograf.
Among them, 89 people (0.21%) have Ventricular tachycardia.

Among these 89 people:
How long have people been on Prograf when they have Ventricular tachycardia? *
- < 1 month: 34.62 %
- 1 - 6 months: 42.31 %
- 6 - 12 months: 3.85 %
- 1 - 2 years: 7.69 %
- 2 - 5 years: 7.69 %
- 5 - 10 years: 0.0 %
- 10+ years: 3.85 %
What is the gender of people who have Ventricular tachycardia when taking Prograf? *
- female: 39.08 %
- male: 60.92 %
What is the age of people who have Ventricular tachycardia when taking Prograf? *
- 0-1: 6.9 %
- 2-9: 1.72 %
- 10-19: 10.34 %
- 20-29: 3.45 %
- 30-39: 12.07 %
- 40-49: 18.97 %
- 50-59: 25.86 %
- 60+: 20.69 %
What are other drugs people take besides Prograf? *
- Prednisone: 17 people, 19.10%
- Prednisolone: 16 people, 17.98%
- Cellcept: 15 people, 16.85%
- Methylprednisolone: 15 people, 16.85%
- Lasix: 13 people, 14.61%
- Heparin: 13 people, 14.61%
- Fluconazole: 12 people, 13.48%
- Furosemide: 12 people, 13.48%
- Aspirin: 11 people, 12.36%
- Solu-Medrol: 10 people, 11.24%
What are other side effects people have besides Ventricular tachycardia? *
- Hypotension (abnormally low blood pressure): 19 people, 21.35%
- Acute Kidney Failure: 18 people, 20.22%
- Cardiac Arrest: 18 people, 20.22%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 17 people, 19.10%
- Fever: 12 people, 13.48%
- Ventricular Fibrillation (abnormally irregular heart rhythm): 12 people, 13.48%
- Cardiac Failure Congestive: 10 people, 11.24%
- Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 10 people, 11.24%
- Cardiogenic Shock (inadequate circulation of blood): 10 people, 11.24%
- Chest Pain: 10 people, 11.24%
What are the existing conditions these people have? *
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 4.49%
- Herpes Zoster: 4 people, 4.49%
- Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 2 people, 2.25%
- Upper Respiratory Tract Infection: 1 person, 1.12%
- Transplant Rejection (a transplant material is not worked): 1 person, 1.12%
- Neck Pain: 1 person, 1.12%
- High Blood Pressure: 1 person, 1.12%
- Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 1 person, 1.12%
- Gastric Disorder (disease of stomach): 1 person, 1.12%
- Fever: 1 person, 1.12%
* Approximation only. Some reports may have incomplete information.
Do you take Prograf and have Ventricular tachycardia?
- Check whether Ventricular tachycardia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Prograf:
- Prograf (42,230 reports)
Ventricular tachycardia treatments and more:
- Ventricular tachycardia (26,755 reports)
How severe was Ventricular tachycardia and when was it recovered:
Expand to all the drugs that have ingredients of tacrolimus:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Prograf:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Ventricular tachycardia:
- Ventricular tachycardia (1,281 drugs)
Browse all the conditions that are associated with Ventricular tachycardia:
- Ventricular tachycardia (2,098 conditions)
Related publications that referenced our studies
- Amit K J Mandal, Umar F Khan, Constantinos G Missouris, "Ventricular tachycardia in a patient with sigmoid volvulus on treatment with donepezil", Clinical Toxicology, 2019 Jan .
- Amit K J Mandal, Umar F Khan, Constantinos G Missouris, "Ventricular tachycardia in a patient with sigmoid volvulus on treatment with donepezil", Clinical Toxicology, 2019 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on tacrolimus (the active ingredients of Prograf) and Prograf (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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