Propofol and Procedural pain - a phase IV clinical study of FDA data

Summary:

Procedural pain is reported as a side effect among people who take Propofol (propofol), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Fentanyl, and have Anaesthesia.

The phase IV clinical study analyzes which people have Procedural pain when taking Propofol. It is created by eHealthMe based on reports of 37,986 people who have side effects when taking Propofol from the FDA, and is updated regularly.

What is Propofol?

Propofol has active ingredients of propofol. It is often used in colonoscopy abnormal. eHealthMe is studying from 38,225 Propofol users. Check the latest studies of Propofol.

What is Procedural pain?

Procedural pain is found to be associated with 992 drugs and 927 conditions by eHealthMe. Check the latest studies of Procedural pain.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

37,986 people reported to have side effects when taking Propofol.
Among them, 76 people (0.2%) have Procedural pain.

Could Propofol cause Procedural pain?

Among these 76 people:

How long have people been on Propofol when they have Procedural pain? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Procedural pain when taking Propofol? *

  • female: 60.81 %
  • male: 39.19 %

What is the age of people who have Procedural pain when taking Propofol? *

  • 0-1: 0.0 %
  • 2-9: 1.69 %
  • 10-19: 8.47 %
  • 20-29: 0.0 %
  • 30-39: 38.98 %
  • 40-49: 16.95 %
  • 50-59: 3.39 %
  • 60+: 30.51 %

What are other drugs people take besides Propofol? *

  1. Fentanyl: 16 people, 21.05%
  2. Pantoprazole: 13 people, 17.11%
  3. Morphine: 13 people, 17.11%
  4. Bactrim: 8 people, 10.53%
  5. Ondansetron: 8 people, 10.53%
  6. Midazolam: 7 people, 9.21%
  7. Promethazine: 7 people, 9.21%
  8. Lidocaine: 6 people, 7.89%
  9. Miralax: 6 people, 7.89%
  10. Metoclopramide: 6 people, 7.89%

What are other side effects people have besides Procedural pain? *

  1. Abdominal Pain: 14 people, 18.42%
  2. Nausea (feeling of having an urge to vomit): 14 people, 18.42%
  3. Weakness: 13 people, 17.11%
  4. Heart Rate Increased: 13 people, 17.11%
  5. Dizziness: 12 people, 15.79%
  6. Diarrhea: 12 people, 15.79%
  7. Stress And Anxiety: 10 people, 13.16%
  8. Hypoaesthesia Oral (reduced sense of touch or sensation in mouth): 10 people, 13.16%
  9. Itching: 10 people, 13.16%
  10. Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem): 10 people, 13.16%

What are the existing conditions these people have? *

  1. Anaesthesia: 20 people, 26.32%
  2. Pain: 18 people, 23.68%
  3. Sedation: 11 people, 14.47%
  4. Nausea (feeling of having an urge to vomit): 10 people, 13.16%
  5. High Blood Pressure: 9 people, 11.84%
  6. General Anaesthesia: 9 people, 11.84%
  7. Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 6 people, 7.89%
  8. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 7.89%
  9. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 6 people, 7.89%
  10. Joint Pain: 6 people, 7.89%

* Approximation only. Some reports may have incomplete information.

Do you take Propofol and have Procedural pain?

- Check whether Procedural pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Propofol:

Procedural pain treatments and more:

How severe was Procedural pain and when was it recovered:

Expand to all the drugs that have ingredients of propofol:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Propofol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Procedural pain:

Browse all the conditions that are associated with Procedural pain:


How the study uses the data?

The study uses data from the FDA. It is based on propofol (the active ingredients of Propofol) and Propofol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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