Propulsid and Adverse event - a phase IV clinical study of FDA data

Summary:

Adverse event is reported as a side effect among people who take Propulsid (cisapride monohydrate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Vioxx, and have Joint pain.

The phase IV clinical study analyzes which people have Adverse event when taking Propulsid. It is created by eHealthMe based on reports of 8,120 people who have side effects when taking Propulsid from the FDA, and is updated regularly.

What is Propulsid?

Propulsid has active ingredients of cisapride monohydrate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 8,130 Propulsid users. Check the latest studies of Propulsid.

What is Adverse event?

Adverse event is found to be associated with 1,672 drugs and 1,674 conditions by eHealthMe. Check the latest studies of Adverse event.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

8,120 people reported to have side effects when taking Propulsid.
Among them, 17 people (0.21%) have Adverse event.

Among these 17 people:

How long have people been on Propulsid when they have Adverse event? *

What is the gender of people who have Adverse event when taking Propulsid? *

female: 76.47 %
male: 23.53 %

What is the age of people who have Adverse event when taking Propulsid? *

What are other drugs people take besides Propulsid? *

What are other side effects people have besides Adverse event? *

Joint Pain: 9 people, 52.94%
Chest Pain: 9 people, 52.94%
Cardiac Failure Congestive: 8 people, 47.06%
Abdominal Pain: 8 people, 47.06%
Back Pain: 8 people, 47.06%
Enlarged Heart: 7 people, 41.18%
Dyspnea (difficult or laboured breathing): 7 people, 41.18%
Hepatic Steatosis (fatty liver disease): 7 people, 41.18%
Mitral Valve Incompetence (inefficient heart valve): 6 people, 35.29%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 6 people, 35.29%

What are the existing conditions these people have? *

Joint Pain: 2 people, 11.76%
Pain: 1 person, 5.88%
Irritable Bowel Syndrome: 1 person, 5.88%
Intestinal Hypomotility (abnormally slow motility, as of the intestine): 1 person, 5.88%
Impaired Gastric Emptying: 1 person, 5.88%
Hepatic Infection: 1 person, 5.88%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 1 person, 5.88%
Gastrointestinal Hypomotility (less activity of the intestinal tract): 1 person, 5.88%
Drooling (drop saliva uncontrollably from the mouth): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Propulsid and have Adverse event?

- Check whether Adverse event is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Propulsid:

Propulsid (8,130 reports)

Adverse event treatments and more:

Adverse event (100,133 reports)

Browse all side effects of Propulsid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Adverse event:

Adverse event (1,672 drugs)

Browse all the conditions that are associated with Adverse event:

Adverse event (1,674 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cisapride monohydrate (the active ingredients of Propulsid) and Propulsid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.