Questran and Cataract - a phase IV clinical study of FDA data

Summary:

Cataract is reported as a side effect among people who take Questran (cholestyramine), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Aspirin, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Cataract when taking Questran. It is created by eHealthMe based on reports of 4,400 people who have side effects when taking Questran from the FDA, and is updated regularly.

What is Questran?

Questran has active ingredients of cholestyramine. It is often used in diarrhea. eHealthMe is studying from 4,490 Questran users. Check the latest studies of Questran.

What is Cataract?

Cataract (clouding of the lens inside the eye) is found to be associated with 1,892 drugs and 2,131 conditions by eHealthMe. Check the latest studies of Cataract.



On Jul, 20, 2026

4,400 people reported to have side effects when taking Questran.
Among them, 18 people (0.41%) have Cataract.

Could Questran cause Cataract?

Among these 18 people:

How long have people been on Questran when they have Cataract? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Cataract when taking Questran? *

  • female: 81.25 %
  • male: 18.75 %

What is the age of people who have Cataract when taking Questran? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 9.09 %
  • 40-49: 0.0 %
  • 50-59: 18.18 %
  • 60+: 72.73 %

What are other drugs people take besides Questran? *

  1. Aspirin: 5 people, 27.78%
  2. Humira: 4 people, 22.22%
  3. Synthroid: 4 people, 22.22%
  4. Fosamax: 4 people, 22.22%
  5. Lasix: 3 people, 16.67%
  6. Norvasc: 3 people, 16.67%
  7. Allopurinol: 3 people, 16.67%
  8. Ambien: 3 people, 16.67%
  9. Nexium: 3 people, 16.67%
  10. Percocet: 3 people, 16.67%

What are other side effects people have besides Cataract? *

  1. High Blood Pressure: 5 people, 27.78%
  2. Pain: 4 people, 22.22%
  3. Fatigue (feeling of tiredness): 4 people, 22.22%
  4. Stress And Anxiety: 3 people, 16.67%
  5. Feeling Abnormal: 3 people, 16.67%
  6. Fall: 3 people, 16.67%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 16.67%
  8. Insomnia (sleeplessness): 3 people, 16.67%
  9. Rashes (redness): 3 people, 16.67%
  10. Scar: 3 people, 16.67%

What are the existing conditions these people have? *

  1. Tremor (trembling or shaking movements in one or more parts of your body): 2 people, 11.11%
  2. Rashes (redness): 2 people, 11.11%
  3. Multiple Myeloma (cancer of the plasma cells): 2 people, 11.11%
  4. Cystitis Interstitial (unknown cause characterized by bladder pain): 2 people, 11.11%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 11.11%
  6. Drowsiness: 1 person, 5.56%
  7. Cartilage Atrophy (cartilage extra growth): 1 person, 5.56%
  8. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 5.56%
  9. Cholangitis (infection of the bile duct): 1 person, 5.56%
  10. Connective Tissue Disorder (any disease that has the connective tissues of the body): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Questran and have Cataract?

- Check whether Cataract is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Questran:

Cataract treatments and more:

How severe was Cataract and when was it recovered:

Expand to all the drugs that have ingredients of cholestyramine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Questran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cataract:

Browse all the conditions that are associated with Cataract:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cholestyramine (the active ingredients of Questran) and Questran (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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