Ramipril and Skin necrosis - a phase IV clinical study of FDA data

Summary:

Skin necrosis is reported as a side effect among people who take Ramipril (ramipril), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Actemra, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Skin necrosis when taking Ramipril. It is created by eHealthMe based on reports of 144,209 people who have side effects when taking Ramipril from the FDA, and is updated regularly.

What is Ramipril?

Ramipril has active ingredients of ramipril. It is often used in high blood pressure. eHealthMe is studying from 147,393 Ramipril users. Check the latest studies of Ramipril.

What is Skin necrosis?

Skin necrosis (skin damage) is found to be associated with 594 drugs and 797 conditions by eHealthMe. Check the latest studies of Skin necrosis.

On May, 01, 2026

144,209 people reported to have side effects when taking Ramipril.
Among them, 200 people (0.14%) have Skin necrosis.

Among these 200 people:

* Approximation only. Some reports may have incomplete information.

Do you take Ramipril and have Skin necrosis?

- Check whether Skin necrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ramipril:

Ramipril (147,393 reports)

Skin necrosis treatments and more:

Skin necrosis (7,151 reports)

How severe was Skin necrosis and when was it recovered:

Skin necrosis in Ramipril

Expand to all the drugs that have ingredients of ramipril:

Skin necrosis and drugs with ingredients of ramipril

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ramipril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Skin necrosis:

Skin necrosis (594 drugs)

Browse all the conditions that are associated with Skin necrosis:

Skin necrosis (797 conditions)

Related publications that referenced our studies

Lee, Y. J., & Park, K. , "Secondary Raynaud’s Phenomenon and Skin Necrosis of Toes in the Paraplegic Patient with Hypertension", Drug safety-case reports, 2018 Jan .
Lee, Y. J., & Park, K. , "Secondary Raynaud’s Phenomenon and Skin Necrosis of Toes in the Paraplegic Patient with Hypertension", Drug safety-case reports, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on ramipril (the active ingredients of Ramipril) and Ramipril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.