Ranitidine and Sinus node dysfunction - a phase IV clinical study of FDA data

Summary:

Sinus node dysfunction is reported as a side effect among people who take Ranitidine (ranitidine), especially for people who are male, 60+ old, also take Coumadin, and have Depression.

The phase IV clinical study analyzes which people have Sinus node dysfunction when taking Ranitidine. It is created by eHealthMe based on reports of 233,168 people who have side effects when taking Ranitidine from the FDA, and is updated regularly.

What is Ranitidine?

Ranitidine has active ingredients of ranitidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 234,474 Ranitidine users. Check the latest studies of Ranitidine.

What is Sinus node dysfunction?

Sinus node dysfunction (a group of abnormal heart rhythms) is found to be associated with 1,262 drugs and 834 conditions by eHealthMe. Check the latest studies of Sinus node dysfunction.

On Oct, 22, 2025

233,168 people reported to have side effects when taking Ranitidine.
Among them, 43 people (0.02%) have Sinus node dysfunction.

Could Ranitidine cause Sinus node dysfunction?

Among these 43 people:

What is the gender of people who have Sinus node dysfunction when taking Ranitidine? *

female: 42.86 %
male: 57.14 %

What is the age of people who have Sinus node dysfunction when taking Ranitidine? *

What are other drugs people take besides Ranitidine? *

What are other side effects people have besides Sinus node dysfunction? *

Bradycardia (abnormally slow heart action): 12 people, 27.91%
Pneumonia: 10 people, 23.26%
Dizziness: 10 people, 23.26%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 10 people, 23.26%
Fatigue (feeling of tiredness): 10 people, 23.26%
Fever: 9 people, 20.93%
Weakness: 8 people, 18.60%
Dyspnea Exertional: 7 people, 16.28%
Cardiac Disorder: 7 people, 16.28%
Sinus Bradycardia (an unusually slow heartbeat due to heart disease): 6 people, 13.95%

What are the existing conditions these people have? *

Depression: 7 people, 16.28%
Stress And Anxiety: 6 people, 13.95%
Nervousness: 6 people, 13.95%
Insomnia (sleeplessness): 6 people, 13.95%
Colorectal Cancer Stage Iii (colon and rectal cancer spreads to lymph nodes): 5 people, 11.63%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 9.30%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 4 people, 9.30%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 6.98%
Multiple Myeloma (cancer of the plasma cells): 3 people, 6.98%
High Blood Pressure: 2 people, 4.65%

* Approximation only. Some reports may have incomplete information.

Do you take Ranitidine and have Sinus node dysfunction?

- Check whether Sinus node dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ranitidine:

Ranitidine (234,474 reports)

Browse all side effects of Ranitidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus node dysfunction:

Sinus node dysfunction (1,262 drugs)

Browse all the conditions that are associated with Sinus node dysfunction:

Sinus node dysfunction (834 conditions)

Drugs similar to Ranitidine and Sinus node dysfunction :

How the study uses the data?

The study uses data from the FDA. It is based on ranitidine (the active ingredients of Ranitidine) and Ranitidine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.