Nexium and Sinus node dysfunction - a phase IV clinical study of FDA data

Summary:

Sinus node dysfunction is reported as a side effect among people who take Nexium (esomeprazole magnesium), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Lasix, and have High blood pressure.

The phase IV clinical study analyzes which people have Sinus node dysfunction when taking Nexium. It is created by eHealthMe based on reports of 240,870 people who have side effects when taking Nexium from the FDA, and is updated regularly.

What is Nexium?

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,675 Nexium users. Check the latest studies of Nexium.

What is Sinus node dysfunction?

Sinus node dysfunction (a group of abnormal heart rhythms) is found to be associated with 1,183 drugs and 840 conditions by eHealthMe. Check the latest studies of Sinus node dysfunction.

On Dec, 09, 2025

240,870 people reported to have side effects when taking Nexium.
Among them, 102 people (0.04%) have Sinus node dysfunction.

Could Nexium cause Sinus node dysfunction?

Among these 102 people:

How long have people been on Nexium when they have Sinus node dysfunction? *

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What is the gender of people who have Sinus node dysfunction when taking Nexium? *

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* Approximation only. Some reports may have incomplete information.

Do you take Nexium and have Sinus node dysfunction?

- Check whether Sinus node dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nexium:

Nexium (245,675 reports)

Sinus node dysfunction treatments and more:

Sinus node dysfunction (4,617 reports)

How severe was Sinus node dysfunction and when was it recovered:

Sinus node dysfunction in Nexium

Expand to all the drugs that have ingredients of esomeprazole magnesium:

Sinus node dysfunction and drugs with ingredients of esomeprazole magnesium (113 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Nexium side effects:

Browse all side effects of Nexium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Sinus node dysfunction:

Browse all the drugs that are associated with Sinus node dysfunction:

Sinus node dysfunction (1,183 drugs)

Common conditions associated with Sinus node dysfunction:

Browse all the conditions that are associated with Sinus node dysfunction:

Sinus node dysfunction (840 conditions)

Drugs similar to Nexium and Sinus node dysfunction :

Related publications that referenced our studies

Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .
Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on esomeprazole magnesium (the active ingredients of Nexium) and Nexium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.