A study for a 20 year old woman who takes Zyrtec, Metformin Hydrochloride, Guanfacine Hydrochloride (an AI-powered real world drug study)
Summary:
153 females aged 20 (±5) who take the same drugs and have adverse effects are studied. This is a phase IV clinical study for a 20 year old female patient who has Adhd, Insulin Resistance, Allergies. The study is created by eHealthMe based on reports from sources including the FDA.
153 females aged 20 (±5) who take Zyrtec, Metformin Hydrochloride, Guanfacine Hydrochloride and have adverse effects are studied.
Number of reports submitted per year:

Information of the patient in this study:
- Age: 20
- Gender: female
What are the drugs?
- Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 114,612 Zyrtec users. Check the latest studies of Zyrtec.
- Metformin hydrochloride has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 58,640 Metformin hydrochloride users. Check the latest studies of Metformin hydrochloride.
- Guanfacine hydrochloride has active ingredients of guanfacine hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 1,211 Guanfacine hydrochloride users. Check the latest studies of Guanfacine hydrochloride.
What are the conditions?
- Adhd (adhd-mental disorders that develop in children) is found to be associated with 595 drugs and 1,375 conditions by eHealthMe. Check the latest studies of Adhd.
- Insulin resistance is found to be associated with 228 drugs and 409 conditions by eHealthMe. Check the latest studies of Insulin resistance.
- Allergies is found to be associated with 2 drugs and 92 conditions by eHealthMe. Check the latest studies of Allergies.
What are the adverse effects?
- Nosebleed (bleeding from nose) is found to be associated with 2,108 drugs and 3,077 conditions by eHealthMe. Check the latest studies of Nosebleed.
Comparison with patient's specific adverse outcomes:
You can check what is more associated with an adverse outcome: a drug mix, a drug, a condition, or a population of certain gender and age. Each patient is different. It is not uncommon that the results can be inconclusive or insignificant.
By the same drug(s):
-
Nosebleed (bleeding from nose):
- among females aged 20 (±5) who take the same drugs: 0.65% (1 of 153)
- among people who take the same drugs, regardless of gender or age: 0.01% (1 of 11,262)
By each condition:
-
people who have Nosebleed with Adhd:
- among females aged 20 (±5) who have Adhd: 0.27% (11 of 4,065)
- among people who have Adhd, regardless of gender or age: 0.31% (271 of 86,052) -
people who have Nosebleed with Insulin Resistance:
- among females aged 20 (±5) who have Insulin Resistance: 0% (0 of 109)
- among people who have Insulin Resistance, regardless of gender or age: 1.42% (28 of 1,967) -
people who have Nosebleed with Allergies:
- among females aged 20 (±5) who have Allergies: 0% (0 of 61)
- among people who have Allergies, regardless of gender or age: 0.46% (17 of 3,731)
By each drug (FDA data only):
-
people who take Guanfacine Hydrochloride and have Nosebleed:
- among females aged 20 (±5) who take Guanfacine Hydrochloride and have side effects: 2.04% (1 of 49)
- among people who take Guanfacine Hydrochloride and have side effects, regardless of gender or age: 0.58% (5 of 861) -
people who take Metformin Hydrochloride and have Nosebleed:
- among females aged 20 (±5) who take Metformin Hydrochloride and have side effects: 0.24% (1 of 420)
- among people who take Metformin Hydrochloride and have side effects, regardless of gender or age: 0.46% (253 of 54,793) -
people who take Zyrtec and have Nosebleed:
- among females aged 20 (±5) who take Zyrtec and have side effects: 0.48% (16 of 3,329)
- among people who take Zyrtec and have side effects, regardless of gender or age: 0.67% (739 of 109,554)
Common drug interactions *:
- Pain : 16 people, 10.46%
- Weight Increased : 16 people, 10.46%
- Dizziness : 15 people, 9.80%
- Nausea (feeling of having an urge to vomit): 13 people, 8.50%
- Fatigue (feeling of tiredness): 12 people, 7.84%
- Dyspnea (difficult or laboured breathing): 12 people, 7.84%
- Drug Ineffective : 11 people, 7.19%
- Abdominal Pain : 11 people, 7.19%
- Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 10 people, 6.54%
- Rashes (redness): 10 people, 6.54%
- Injury : 10 people, 6.54%
- Weakness : 9 people, 5.88%
- Asthma : 9 people, 5.88%
- Malaise (a feeling of general discomfort or uneasiness): 8 people, 5.23%
- Joint Pain : 8 people, 5.23%
- Itching : 8 people, 5.23%
- Nausea And Vomiting : 8 people, 5.23%
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 8 people, 5.23%
- Suicidal Ideation : 8 people, 5.23%
- Gallstones (stone formation by bile component): 7 people, 4.58%
Common co-existing conditions *:
You may use this to check any potential undetected conditions.
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 18 people, 11.76%
- Depression : 14 people, 9.15%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 6.54%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 4.58%
- Hypersensitivity : 7 people, 4.58%
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 7 people, 4.58%
- Pain : 7 people, 4.58%
- Immunodeficiency Common Variable : 6 people, 3.92%
- Psychotic Disorder : 6 people, 3.92%
- Cystic Fibrosis (disease of the secretary glands): 6 people, 3.92%
- Weight Loss : 6 people, 3.92%
- Drowsiness : 5 people, 3.27%
- Acne (skin problems that cause pimples): 5 people, 3.27%
- Glucose Tolerance Impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis): 4 people, 2.61%
- Menstruation Irregular : 4 people, 2.61%
- Asthma : 4 people, 2.61%
- Schizoaffective Disorder Bipolar Type (mental illness featuring schizophrenia and a mood disorder with mania): 4 people, 2.61%
- Migraine (headache): 3 people, 1.96%
- Anger : 3 people, 1.96%
- Bipolar Disorder (mood disorder): 3 people, 1.96%
Common co-used drugs *:
You may use this to check any potential interacting drugs.
- Prilosec (20 people, 13.07%)
- Melatonin (18 people, 11.76%)
- Yasmin (17 people, 11.11%)
- Singulair (17 people, 11.11%)
- Ibuprofen (17 people, 11.11%)
- Xyrem (16 people, 10.46%)
- Lamotrigine (16 people, 10.46%)
- Flonase (15 people, 9.80%)
- Miralax (13 people, 8.50%)
- Escitalopram (13 people, 8.50%)
- Zantac (13 people, 8.50%)
- Vitamin D3 (13 people, 8.50%)
- Fluoxetine (12 people, 7.84%)
- Famotidine (11 people, 7.19%)
- Wellbutrin (11 people, 7.19%)
- Epipen (10 people, 6.54%)
- Tylenol (10 people, 6.54%)
- Lexapro (10 people, 6.54%)
- Lyrica (10 people, 6.54%)
- Yaz (10 people, 6.54%)
Drug effectiveness *:
Zyrtec:
- not at all: 0 %
- somewhat: 0 %
- moderate: 0 %
- high: 100 %
- very high: 0 %
Metformin Hydrochloride:
- not at all: 0 %
- somewhat: 50 %
- moderate: 50 %
- high: 0 %
- very high: 0 %
Guanfacine Hydrochloride:
n/a
* Some reports may have incomplete information.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related studies
Drug side effects in long term, by gender and age:
- Guanfacine hydrochloride: 1,211 reports
- Metformin hydrochloride: 58,640 reports
- Zyrtec: 114,612 reports
Treatments, associated medications and conditions:
- Adhd: 120,276 reports
- Allergies: 15,344 reports
- Insulin resistance: 4,835 reports
- Nosebleed: 92,073 reports
Drug side effects:
- Zyrtec and Nosebleed (739 reports)
- Metformin hydrochloride and Nosebleed (253 reports)
- Guanfacine hydrochloride and Nosebleed
Drug interactions:
- Zyrtec and Metformin hydrochloride drug interaction (797 reports)
- Zyrtec and Guanfacine hydrochloride drug interaction (21 reports)
- Metformin hydrochloride and Guanfacine hydrochloride drug interaction (10 reports)
Symptoms:
- Adhd and Nosebleed (271 reports)
- Insulin resistance and Nosebleed (28 reports)
- Allergies and Nosebleed (17 reports)
Drugs that are associated with:
- Nosebleed: 2,108 drugs
Conditions that are associated with:
- Nosebleed: 3,077 conditions
How the phase IV clinical study uses the data?
The study is based on gender, age, active ingredients of any drugs used. Other drugs that have the same active ingredients (e.g. generic drugs) are considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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