A study for a 57 year old man who takes Amlodipine, Lopurin (an AI-powered real world drug study)

Summary:

2,390 males aged 57 (±5) who take the same drugs and have adverse effects are studied. This is a phase IV clinical study for a 57 year old male patient who has Hypertension, Gout. The study is created by eHealthMe based on reports from sources including the FDA.


On Jan, 25, 2026

2,390 males aged 57 (±5) who take Amlodipine, Lopurin and have adverse effects are studied.


Number of reports submitted per year:

Amlodipine, Lopurin for a 57-year old man.

Information of the patient in this study:

  • Age: 57
  • Gender: male

What are the drugs?

What are the conditions?

What are the adverse effects?


Comparison with patient's specific adverse outcomes:

You can check what is more associated with an adverse outcome: a drug mix, a drug, a condition, or a population of certain gender and age. Each patient is different. It is not uncommon that the results can be inconclusive or insignificant.

By the same drug(s):

  • Kidney Stones:
    - among males aged 57 (±5) who take the same drugs: 0.59% (14 of 2,390)
    - among people who take the same drugs, regardless of gender or age: 0.05% (14 of 25,915)

By each condition:

  • people who have Kidney Stones with Hypertension:
    - among males aged 57 (±5) who have Hypertension: 0.43% (214 of 50,280)
    - among people who have Hypertension, regardless of gender or age: 0.43% (2,644 of 608,860)
  • people who have Kidney Stones with Gout:
    - among males aged 57 (±5) who have Gout: 0.74% (28 of 3,773)
    - among people who have Gout, regardless of gender or age: 0.63% (202 of 32,032)

By each drug (FDA data only):

  • people who take Amlodipine and have Kidney Stones:
    - among males aged 57 (±5) who take Amlodipine and have side effects: 0.4% (110 of 27,306)
    - among people who take Amlodipine and have side effects, regardless of gender or age: 0.4% (1,377 of 346,928)
  • people who take Lopurin and have Kidney Stones:
    - among males aged 57 (±5) who take Lopurin and have side effects: 0.51% (89 of 17,412)
    - among people who take Lopurin and have side effects, regardless of gender or age: 0.49% (925 of 188,185)

Common drug interactions *:

  1. Acute Kidney Failure : 276 people, 11.55%
  2. Chronic Kidney Disease : 247 people, 10.33%
  3. Pain : 172 people, 7.20%
  4. Dizziness : 153 people, 6.40%
  5. Dyspnea (difficult or laboured breathing): 147 people, 6.15%
  6. Cough : 143 people, 5.98%
  7. Fever : 138 people, 5.77%
  8. Diarrhea : 134 people, 5.61%
  9. Stress And Anxiety : 131 people, 5.48%
  10. Fatigue (feeling of tiredness): 120 people, 5.02%
  11. Nausea (feeling of having an urge to vomit): 113 people, 4.73%
  12. Weakness : 106 people, 4.44%
  13. Chest Pain : 104 people, 4.35%
  14. Joint Pain : 103 people, 4.31%
  15. Drug Ineffective : 98 people, 4.10%
  16. Memory Loss : 97 people, 4.06%
  17. Fall : 94 people, 3.93%
  18. Asthma : 92 people, 3.85%
  19. Insomnia (sleeplessness): 87 people, 3.64%
  20. Eosinophilia (eosinophil count in the peripheral blood exceeds): 87 people, 3.64%

Common co-existing conditions *:

You may use this to check any potential undetected conditions.

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 224 people, 9.37%
  2. Pain : 201 people, 8.41%
  3. High Blood Cholesterol : 193 people, 8.08%
  4. Diabetes : 169 people, 7.07%
  5. Multiple Myeloma (cancer of the plasma cells): 159 people, 6.65%
  6. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 97 people, 4.06%
  7. Depression : 91 people, 3.81%
  8. Type 2 Diabetes : 87 people, 3.64%
  9. Hyperlipidaemia (presence of excess lipids in the blood): 83 people, 3.47%
  10. Stress And Anxiety : 73 people, 3.05%
  11. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 66 people, 2.76%
  12. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 63 people, 2.64%
  13. Arthritis (form of joint disorder that involves inflammation of one or more joints): 62 people, 2.59%
  14. Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 55 people, 2.30%
  15. Indigestion : 54 people, 2.26%
  16. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 52 people, 2.18%
  17. Infection : 51 people, 2.13%
  18. Renal Cell Carcinoma (a kidney cancer): 51 people, 2.13%
  19. Cardiac Disorder : 50 people, 2.09%
  20. Fluid Retention (an abnormal accumulation of fluid in the blood): 45 people, 1.88%

Common co-used drugs *:

You may use this to check any potential interacting drugs.

  1. Metformin (269 people, 11.26%)
  2. Aspirin (257 people, 10.75%)
  3. Nexium (237 people, 9.92%)
  4. Lipitor (202 people, 8.45%)
  5. Prilosec (185 people, 7.74%)
  6. Lasix (178 people, 7.45%)
  7. Pantoprazole (170 people, 7.11%)
  8. Tamsulosin (161 people, 6.74%)
  9. Vitamin D3 (152 people, 6.36%)
  10. Prednisone (145 people, 6.07%)
  11. Protonix (143 people, 5.98%)
  12. Furosemide (136 people, 5.69%)
  13. Lisinopril (135 people, 5.65%)
  14. Lorazepam (133 people, 5.56%)
  15. Tylenol (130 people, 5.44%)
  16. Plavix (125 people, 5.23%)
  17. Prevacid (114 people, 4.77%)
  18. Oxycodone (114 people, 4.77%)
  19. Rosuvastatin Calcium (114 people, 4.77%)
  20. Nexium 24hr (112 people, 4.69%)

Drug effectiveness *:

Amlodipine:
  • not at all: 0 %
  • somewhat: 0 %
  • moderate: 33.33 %
  • high: 66.67 %
  • very high: 0 %
Lopurin:
  • not at all: 0 %
  • somewhat: 0 %
  • moderate: 33.33 %
  • high: 66.67 %
  • very high: 0 %

* Some reports may have incomplete information.


How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

Drug side effects in long term, by gender and age:

Treatments, associated medications and conditions:

Drug side effects:

Drug interactions:

Symptoms:

Drugs that are associated with:

Conditions that are associated with:

How the phase IV clinical study uses the data?

The study is based on gender, age, active ingredients of any drugs used. Other drugs that have the same active ingredients (e.g. generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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