Ranolazine and Tinnitus aggravated - a phase IV clinical study of FDA data

Summary:

Tinnitus aggravated is reported as a side effect among people who take Ranolazine (ranolazine), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Aspirin, and have Stable angina.

The phase IV clinical study analyzes which people have Tinnitus aggravated when taking Ranolazine. It is created by eHealthMe based on reports of 9,903 people who have side effects when taking Ranolazine from the FDA, and is updated regularly.

What is Ranolazine?

Ranolazine has active ingredients of ranolazine. eHealthMe is studying from 9,939 Ranolazine users. Check the latest studies of Ranolazine.

What is Tinnitus aggravated?

Tinnitus aggravated (ringing in the ears) is found to be associated with 1,556 drugs and 632 conditions by eHealthMe. Check the latest studies of Tinnitus aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

9,903 people reported to have side effects when taking Ranolazine.
Among them, 21 people (0.21%) have Tinnitus aggravated.

Could Ranolazine cause Tinnitus aggravated?

Among these 21 people:

How long have people been on Ranolazine when they have Tinnitus aggravated? *

What is the gender of people who have Tinnitus aggravated when taking Ranolazine? *

female: 47.37 %
male: 52.63 %

What is the age of people who have Tinnitus aggravated when taking Ranolazine? *

What are other drugs people take besides Ranolazine? *

Aspirin: 5 people, 23.81%
Clopidogrel: 4 people, 19.05%
Nitroglycerin: 3 people, 14.29%
Isosorbide Mononitrate: 3 people, 14.29%
Lisinopril: 3 people, 14.29%
Metformin: 3 people, 14.29%
Zopiclone: 2 people, 9.52%
Adcal: 2 people, 9.52%
Anastrozole: 2 people, 9.52%
Chloramphenicol: 2 people, 9.52%

What are other side effects people have besides Tinnitus aggravated? *

Weakness: 7 people, 33.33%
Nausea (feeling of having an urge to vomit): 5 people, 23.81%
Dizziness: 4 people, 19.05%
Constipation: 4 people, 19.05%
Dyspnea (difficult or laboured breathing): 4 people, 19.05%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 4 people, 19.05%
Coronary Artery Occlusion (complete obstruction of blood flow in a coronary artery): 3 people, 14.29%
Coordination Abnormal (abnormal movement): 3 people, 14.29%
Memory Loss: 3 people, 14.29%
Stress And Anxiety: 3 people, 14.29%

What are the existing conditions these people have? *

Stable Angina (a constant chest pain): 7 people, 33.33%
High Blood Cholesterol: 3 people, 14.29%
High Density Lipoprotein Decreased: 2 people, 9.52%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 4.76%
Prinzmetal Angina (cardiac chest pain at rest that occurs in cycles): 1 person, 4.76%
Glaucoma (increased fluid pressure in the eye with vision loss): 1 person, 4.76%
Endocrine Ophthalmopathy (increased water content of retroocular orbital tissues; associated with thyroid disease, usually hyperthyroidism): 1 person, 4.76%
Dyspnea (difficult or laboured breathing): 1 person, 4.76%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Ranolazine and have Tinnitus aggravated?

- Check whether Tinnitus aggravated is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ranolazine:

Ranolazine (9,939 reports)

Browse all side effects of Ranolazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tinnitus aggravated:

Tinnitus aggravated (1,556 drugs)

Browse all the conditions that are associated with Tinnitus aggravated:

Tinnitus aggravated (632 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ranolazine (the active ingredients of Ranolazine) and Ranolazine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.