Effient and Atrial fibrillation/flutter - a phase IV clinical study of FDA data

Summary:

Atrial fibrillation/flutter is reported as a side effect among people who take Effient (prasugrel hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Xarelto, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Atrial fibrillation/flutter when taking Effient. It is created by eHealthMe based on reports of 9,155 people who have side effects when taking Effient from the FDA, and is updated regularly.

What is Effient?

Effient has active ingredients of prasugrel hydrochloride. It is often used in stent. eHealthMe is studying from 9,482 Effient users. Check the latest studies of Effient.

What is Atrial fibrillation/flutter?

Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles) is found to be associated with 2,362 drugs and 3,844 conditions by eHealthMe. Check the latest studies of Atrial fibrillation/flutter.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

9,155 people reported to have side effects when taking Effient.
Among them, 76 people (0.83%) have Atrial fibrillation/flutter.

Could Effient cause Atrial fibrillation/flutter?

Among these 76 people:

How long have people been on Effient when they have Atrial fibrillation/flutter? *

What is the gender of people who have Atrial fibrillation/flutter when taking Effient? *

female: 37.5 %
male: 62.5 %

What is the age of people who have Atrial fibrillation/flutter when taking Effient? *

What are other drugs people take besides Effient? *

What are other side effects people have besides Atrial fibrillation/flutter? *

Cardiac Disorder: 12 people, 15.79%
Stable Angina (a constant chest pain): 12 people, 15.79%
Chest Pain: 12 people, 15.79%
Arrhythmias (irregular heartbeat): 12 people, 15.79%
Heart Rate Decreased: 11 people, 14.47%
Urinary Tract Infection: 10 people, 13.16%
Joint Pain: 10 people, 13.16%
Nosebleed (bleeding from nose): 10 people, 13.16%
High Blood Cholesterol: 10 people, 13.16%
Bacterial Infection: 9 people, 11.84%

What are the existing conditions these people have? *

High Blood Cholesterol: 13 people, 17.11%
Back Pain: 9 people, 11.84%
Infection: 6 people, 7.89%
Thyroid Diseases: 6 people, 7.89%
High Blood Pressure: 5 people, 6.58%
Diabetes: 5 people, 6.58%
Percutaneous Coronary Intervention: 4 people, 5.26%
Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 5.26%
Rickets (softening of bones): 3 people, 3.95%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 3.95%

* Approximation only. Some reports may have incomplete information.

Do you take Effient and have Atrial fibrillation/flutter?

- Check whether Atrial fibrillation/flutter is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Effient:

Effient (9,482 reports)

Browse all side effects of Effient:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Atrial fibrillation/flutter:

Atrial fibrillation/flutter (2,362 drugs)

Browse all the conditions that are associated with Atrial fibrillation/flutter:

Atrial fibrillation/flutter (3,844 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on prasugrel hydrochloride (the active ingredients of Effient) and Effient (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.