Reclast and Seizures - a phase IV clinical study of FDA data
Summary:
Seizures is reported as a side effect among people who take Reclast (zoledronic acid), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Vitamin D3, and have Bone disorder.
The phase IV clinical study analyzes which people have Seizures when taking Reclast. It is created by eHealthMe based on reports of 15,446 people who have side effects when taking Reclast from the FDA, and is updated regularly.
What is Reclast?
Reclast has active ingredients of zoledronic acid. It is often used in osteoporosis. eHealthMe is studying from 15,774 Reclast users. Check the latest studies of Reclast.
What is Seizures?
Seizures (abnormal excessive or synchronous neuronal activity in the brain) is found to be associated with 1,996 drugs and 2,277 conditions by eHealthMe. Check the latest studies of Seizures.
15,446 people reported to have side effects when taking Reclast.
Among them, 41 people (0.27%) have Seizures.

Among these 41 people:
How long have people been on Reclast when they have Seizures? *
- < 1 month: 100 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Seizures when taking Reclast? *
- female: 97.44 %
- male: 2.56 %
What is the age of people who have Seizures when taking Reclast? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 5 %
- 40-49: 10 %
- 50-59: 5 %
- 60+: 80 %
What are other drugs people take besides Reclast? *
- Vitamin D3: 13 people, 31.71%
- Cymbalta: 10 people, 24.39%
- Nasonex: 9 people, 21.95%
- Inderal: 8 people, 19.51%
- Heparin: 8 people, 19.51%
- Pyridoxine: 8 people, 19.51%
- Novolog: 8 people, 19.51%
- Ondansetron: 8 people, 19.51%
- Cardizem: 8 people, 19.51%
- Calcium: 8 people, 19.51%
What are other side effects people have besides Seizures? *
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 16 people, 39.02%
- Malaise (a feeling of general discomfort or uneasiness): 11 people, 26.83%
- Weakness: 10 people, 24.39%
- Loss Of Consciousness: 10 people, 24.39%
- Pain: 8 people, 19.51%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 19.51%
- Blood Magnesium Decreased: 8 people, 19.51%
- Fall: 8 people, 19.51%
- Nausea (feeling of having an urge to vomit): 7 people, 17.07%
- Urinary Tract Infection: 7 people, 17.07%
What are the existing conditions these people have? *
- Bone Disorder: 7 people, 17.07%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 9.76%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 7.32%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 3 people, 7.32%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 7.32%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 4.88%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 4.88%
- Drowsiness: 2 people, 4.88%
- Gait Disturbance: 2 people, 4.88%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 4.88%
* Approximation only. Some reports may have incomplete information.
Do you take Reclast and have Seizures?
- Check whether Seizures is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Reclast:
- Reclast (15,774 reports)
Seizures treatments and more:
- Seizures (150,179 reports)
How severe was Seizures and when was it recovered:
Expand to all the drugs that have ingredients of zoledronic acid:
- Seizures and drugs with ingredients of zoledronic acid (275 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Reclast:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Seizures:
- Seizures (1,996 drugs)
Browse all the conditions that are associated with Seizures:
- Seizures (2,277 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on zoledronic acid (the active ingredients of Reclast) and Reclast (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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