Remeron and Bone loss - a phase IV clinical study of FDA data

Summary:

Bone loss is reported as a side effect among people who take Remeron (mirtazapine), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Zometa, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Bone loss when taking Remeron. It is created by eHealthMe based on reports of 24,977 people who have side effects when taking Remeron from the FDA, and is updated regularly.

What is Remeron?

Remeron has active ingredients of mirtazapine. It is often used in depression. eHealthMe is studying from 26,474 Remeron users. Check the latest studies of Remeron.

What is Bone loss?

Bone loss is found to be associated with 697 drugs and 557 conditions by eHealthMe. Check the latest studies of Bone loss.

On Jul, 12, 2026

24,977 people reported to have side effects when taking Remeron.
Among them, 54 people (0.22%) have Bone loss.

Among these 54 people:

How long have people been on Remeron when they have Bone loss? *

What is the gender of people who have Bone loss when taking Remeron? *

female: 83.33 %
male: 16.67 %

What is the age of people who have Bone loss when taking Remeron? *

What are other drugs people take besides Remeron? *

What are other side effects people have besides Bone loss? *

Osteonecrosis Of Jaw (death of bone of jaw): 46 people, 85.19%
Pain: 46 people, 85.19%
Injury: 40 people, 74.07%
Infection: 39 people, 72.22%
Physical Disability: 37 people, 68.52%
Pain In Jaw: 34 people, 62.96%
Dyspnea (difficult or laboured breathing): 34 people, 62.96%
Diarrhea: 32 people, 59.26%
High Blood Cholesterol: 32 people, 59.26%
Joint Pain: 32 people, 59.26%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 15 people, 27.78%
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 13 people, 24.07%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 13 people, 24.07%
Neoplasm Malignant (cancer tumour): 13 people, 24.07%
Sleep Apnea Syndrome: 10 people, 18.52%
Metastases To Bone (cancer spreads to bone): 9 people, 16.67%
Osteopenia (a condition where bone mineral density is lower than normal): 6 people, 11.11%
Oedema (fluid collection in tissue): 4 people, 7.41%
Nausea (feeling of having an urge to vomit): 4 people, 7.41%
Oral Pain: 4 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Remeron and have Bone loss?

- Check whether Bone loss is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Remeron:

Remeron (26,474 reports)

Bone loss treatments and more:

Bone loss (27,142 reports)

Browse all side effects of Remeron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bone loss:

Bone loss (697 drugs)

Browse all the conditions that are associated with Bone loss:

Bone loss (557 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on mirtazapine (the active ingredients of Remeron) and Remeron (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.