Renagel and Scleroma - a phase IV clinical study of FDA data

Summary:

Scleroma is reported as a side effect among people who take Renagel (sevelamer hydrochloride), especially for people who are female, 50-59 old, also take Magnevist, and have Nuclear magnetic resonance imaging brain.

The phase IV clinical study analyzes which people have Scleroma when taking Renagel. It is created by eHealthMe based on reports of 8,224 people who have side effects when taking Renagel from the FDA, and is updated regularly.

What is Renagel?

Renagel has active ingredients of sevelamer hydrochloride. eHealthMe is studying from 8,246 Renagel users. Check the latest studies of Renagel.

What is Scleroma?

Scleroma (a hardened patch of tissue in the skin or mucous membranes) is found to be associated with 306 drugs and 493 conditions by eHealthMe. Check the latest studies of Scleroma.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

8,224 people reported to have side effects when taking Renagel.
Among them, 35 people (0.43%) have Scleroma.

Among these 35 people:

What is the gender of people who have Scleroma when taking Renagel? *

female: 68.57 %
male: 31.43 %

What is the age of people who have Scleroma when taking Renagel? *

What are other drugs people take besides Renagel? *

What are other side effects people have besides Scleroma? *

Nephrogenic Systemic Fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease): 35 people, 100.00%
Pain: 29 people, 82.86%
Skin Discoloration: 27 people, 77.14%
Skin Hypertrophy (skin cells enlarges): 27 people, 77.14%
Skin Fibrosis (fibrous tissue formation on skin): 26 people, 74.29%
Oedema Peripheral (superficial swelling): 25 people, 71.43%
Mobility Decreased (ability to move is reduced): 24 people, 68.57%
Weakness: 22 people, 62.86%
Skin Tightness: 20 people, 57.14%
Deformity (disfigurement): 19 people, 54.29%

What are the existing conditions these people have? *

Nuclear Magnetic Resonance Imaging Brain: 10 people, 28.57%
Pain: 5 people, 14.29%
Renal Disorder (kidney disease): 4 people, 11.43%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 11.43%
Anaemia (lack of blood): 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

Do you take Renagel and have Scleroma?

- Check whether Scleroma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Renagel:

Renagel (8,246 reports)

Scleroma treatments and more:

Scleroma (2,214 reports)

Browse all side effects of Renagel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Scleroma:

Scleroma (306 drugs)

Browse all the conditions that are associated with Scleroma:

Scleroma (493 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sevelamer hydrochloride (the active ingredients of Renagel) and Renagel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.