Repatha and Ear discomfort - a phase IV clinical study of FDA data

Summary:

Ear discomfort is reported as a side effect among people who take Repatha (evolocumab), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Metformin, and have Hyperlipidaemia.

The phase IV clinical study analyzes which people have Ear discomfort when taking Repatha. It is created by eHealthMe based on reports of 155,838 people who have side effects when taking Repatha from the FDA, and is updated regularly.

What is Repatha?

Repatha has active ingredients of evolocumab. It is often used in high blood cholesterol. eHealthMe is studying from 156,258 Repatha users. Check the latest studies of Repatha.

What is Ear discomfort?

Ear discomfort is found to be associated with 821 drugs and 1,357 conditions by eHealthMe. Check the latest studies of Ear discomfort.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

155,838 people reported to have side effects when taking Repatha.
Among them, 74 people (0.05%) have Ear discomfort.

Among these 74 people:

How long have people been on Repatha when they have Ear discomfort? *

What is the gender of people who have Ear discomfort when taking Repatha? *

female: 53.42 %
male: 46.58 %

What is the age of people who have Ear discomfort when taking Repatha? *

What are other drugs people take besides Repatha? *

What are other side effects people have besides Ear discomfort? *

Headache (pain in head): 15 people, 20.27%
Dizziness: 14 people, 18.92%
Rhinorrhea (watery mucus discharge from the nose): 13 people, 17.57%
Ear Pain: 10 people, 13.51%
Back Pain: 10 people, 13.51%
Sinusitis (inflammation of sinus): 10 people, 13.51%
High Blood Pressure: 9 people, 12.16%
Oropharyngeal Pain: 9 people, 12.16%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 9 people, 12.16%
Muscle Aches (muscle pain): 8 people, 10.81%

What are the existing conditions these people have? *

Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 6.76%
Low Density Lipoprotein Increased (cholesterol increased in blood): 3 people, 4.05%
High Blood Pressure: 3 people, 4.05%
Arteriosclerosis Coronary Artery (thickening and hardening of arteries- coronary artery): 2 people, 2.70%
Pain: 2 people, 2.70%
Atherosclerosis (disorder of the arteries): 2 people, 2.70%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 2.70%
Type 2 Diabetes: 2 people, 2.70%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 1.35%
Blood Glucose Increased: 1 person, 1.35%

* Approximation only. Some reports may have incomplete information.

Do you take Repatha and have Ear discomfort?

- Check whether Ear discomfort is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Repatha:

Repatha (156,258 reports)

Ear discomfort treatments and more:

Ear discomfort (11,548 reports)

Browse all side effects of Repatha:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ear discomfort:

Ear discomfort (821 drugs)

Browse all the conditions that are associated with Ear discomfort:

Ear discomfort (1,357 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on evolocumab (the active ingredients of Repatha) and Repatha (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.