Repatha and Exostosis - a phase IV clinical study of FDA data

Summary:

Exostosis is reported as a side effect among people who take Repatha (evolocumab), especially for people who are male, 60+ old, also take Aspirin, and have Pneumothorax.

The phase IV clinical study analyzes which people have Exostosis when taking Repatha. It is created by eHealthMe based on reports of 155,838 people who have side effects when taking Repatha from the FDA, and is updated regularly.

What is Repatha?

Repatha has active ingredients of evolocumab. It is often used in high blood cholesterol. eHealthMe is studying from 156,258 Repatha users. Check the latest studies of Repatha.

What is Exostosis?

Exostosis (formation of new bone on the surface of a bone) is found to be associated with 1,087 drugs and 929 conditions by eHealthMe. Check the latest studies of Exostosis.

On Aug, 09, 2026

155,838 people reported to have side effects when taking Repatha.
Among them, 172 people (0.11%) have Exostosis.

Among these 172 people:

* Approximation only. Some reports may have incomplete information.

Do you take Repatha and have Exostosis?

- Check whether Exostosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Repatha:

Repatha (156,258 reports)

Exostosis treatments and more:

Exostosis (13,639 reports)

How severe was Exostosis and when was it recovered:

Exostosis in Repatha

Expand to all the drugs that have ingredients of evolocumab:

Exostosis and drugs with ingredients of evolocumab (191 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Repatha:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Exostosis:

Exostosis (1,087 drugs)

Browse all the conditions that are associated with Exostosis:

Exostosis (929 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on evolocumab (the active ingredients of Repatha) and Repatha (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.