Requip and Muscle atrophy - a phase IV clinical study of FDA data

Summary:

Muscle atrophy is reported as a side effect among people who take Requip (ropinirole hydrochloride), especially for people who are female, 60+ old, also take Cozaar, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Muscle atrophy when taking Requip. It is created by eHealthMe based on reports of 21,866 people who have side effects when taking Requip from the FDA, and is updated regularly.

What is Requip?

Requip has active ingredients of ropinirole hydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 22,950 Requip users. Check the latest studies of Requip.

What is Muscle atrophy?

Muscle atrophy (a decrease in the mass of the muscle) is found to be associated with 1,056 drugs and 1,953 conditions by eHealthMe. Check the latest studies of Muscle atrophy.



On Jul, 13, 2026

21,866 people reported to have side effects when taking Requip.
Among them, 20 people (0.09%) have Muscle atrophy.

Could Requip cause Muscle atrophy?

Among these 20 people:

What is the gender of people who have Muscle atrophy when taking Requip? *

  • female: 70 %
  • male: 30 %

What is the age of people who have Muscle atrophy when taking Requip? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 5.88 %
  • 50-59: 17.65 %
  • 60+: 76.47 %

What are other drugs people take besides Requip? *

  1. Lipitor: 8 people, 40.00%
  2. Neurontin: 8 people, 40.00%
  3. Biotin: 8 people, 40.00%
  4. Cozaar: 8 people, 40.00%
  5. Zoloft: 7 people, 35.00%
  6. Zofran: 6 people, 30.00%
  7. Provigil: 6 people, 30.00%
  8. Norvasc: 5 people, 25.00%
  9. Pulmicort Flexhaler: 5 people, 25.00%
  10. Glucophage: 5 people, 25.00%

What are other side effects people have besides Muscle atrophy? *

  1. Feeling Abnormal: 8 people, 40.00%
  2. Weakness: 7 people, 35.00%
  3. Dizziness: 6 people, 30.00%
  4. Fatigue (feeling of tiredness): 6 people, 30.00%
  5. Eyelid Ptosis (falling of the upper or lower eyelid): 6 people, 30.00%
  6. Speech Disorder: 6 people, 30.00%
  7. Common Peroneal Nerve Dysfunction (dysfunction of nerve controlling movement and sensation to the lower leg, foot and toes): 6 people, 30.00%
  8. Blood Creatine Phosphokinase Increased: 6 people, 30.00%
  9. Depression: 5 people, 25.00%
  10. Neuropathy Peripheral (surface nerve damage): 5 people, 25.00%

What are the existing conditions these people have? *

  1. High Blood Cholesterol: 8 people, 40.00%
  2. High Blood Pressure: 6 people, 30.00%
  3. Blood Pressure Abnormal: 6 people, 30.00%
  4. Nausea And Vomiting: 5 people, 25.00%
  5. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 5 people, 25.00%
  6. Type 2 Diabetes: 5 people, 25.00%
  7. Nausea (feeling of having an urge to vomit): 5 people, 25.00%
  8. Wheezing (a high-pitched whistling sound made while you breath): 5 people, 25.00%
  9. Neoplasm Malignant (cancer tumour): 5 people, 25.00%
  10. Oedema Peripheral (superficial swelling): 5 people, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Requip and have Muscle atrophy?

- Check whether Muscle atrophy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Requip:

Muscle atrophy treatments and more:

How severe was Muscle atrophy and when was it recovered:

Expand to all the drugs that have ingredients of ropinirole hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Requip:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle atrophy:

Browse all the conditions that are associated with Muscle atrophy:


How the study uses the data?

The study uses data from the FDA. It is based on ropinirole hydrochloride (the active ingredients of Requip) and Requip (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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