Rexulti and Gambling - a phase IV clinical study of FDA data

Summary:

Gambling is reported as a side effect among people who take Rexulti (brexpiprazole), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Cymbalta, and have Bipolar disorder.

The phase IV clinical study analyzes which people have Gambling when taking Rexulti. It is created by eHealthMe based on reports of 13,206 people who have side effects when taking Rexulti from the FDA, and is updated regularly.

What is Rexulti?

Rexulti has active ingredients of brexpiprazole. It is often used in major depression. eHealthMe is studying from 13,394 Rexulti users. Check the latest studies of Rexulti.

What is Gambling?

Gambling is found to be associated with 63 drugs and 183 conditions by eHealthMe. Check the latest studies of Gambling.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 17, 2026

13,206 people reported to have side effects when taking Rexulti.
Among them, 32 people (0.24%) have Gambling.

Among these 32 people:

How long have people been on Rexulti when they have Gambling? *

What is the gender of people who have Gambling when taking Rexulti? *

female: 36.67 %
male: 63.33 %

What is the age of people who have Gambling when taking Rexulti? *

What are other drugs people take besides Rexulti? *

What are other side effects people have besides Gambling? *

Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 7 people, 21.88%
Irritability: 4 people, 12.50%
Mood Swings (an extreme or rapid change in mood): 4 people, 12.50%
Sleep Disorder: 3 people, 9.38%
Compulsive Shopping: 3 people, 9.38%
Impulsive Behavior: 3 people, 9.38%
Hypomania (a mild form of mania, marked by elation and hyperactivity): 3 people, 9.38%
Obsessive Thoughts (intrusive thoughts that produce uneasiness, apprehension, fear, or worry): 2 people, 6.25%
Compulsions (performing an act persistently and repetitively): 2 people, 6.25%
Libido Increased (increased sexual urge to have sex): 2 people, 6.25%

What are the existing conditions these people have? *

Bipolar Disorder (mood disorder): 6 people, 18.75%
Depression: 5 people, 15.62%
Stress And Anxiety: 2 people, 6.25%
Panic Disorder: 2 people, 6.25%
Insomnia (sleeplessness): 2 people, 6.25%
Psychotic Disorder: 1 person, 3.12%
Post-Traumatic Stress Disorder: 1 person, 3.12%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 1 person, 3.12%
Bipolar Ii Disorder (characterized by at least one episode of hypomania and at least one episode of major depression): 1 person, 3.12%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 1 person, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Rexulti and have Gambling?

- Check whether Gambling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rexulti:

Rexulti (13,394 reports)

Gambling treatments and more:

Gambling (1,431 reports)

Browse all side effects of Rexulti:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gambling:

Gambling (63 drugs)

Browse all the conditions that are associated with Gambling:

Gambling (183 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on brexpiprazole (the active ingredients of Rexulti) and Rexulti (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.