Riboflavin and Death - a phase IV clinical study of FDA data

Summary:

Death is reported as a side effect among people who take Riboflavin (riboflavin (vitamin b2)), especially for people who are male, 60+ old, also take Allopurinol, and have Constipation.

The study is created by eHealthMe based on reports of 2,771 people who have side effects when taking Riboflavin from the FDA, and is updated regularly.

What is Riboflavin?

Riboflavin has active ingredients of riboflavin (vitamin b2). It is often used in migraine. eHealthMe is studying from 2,869 Riboflavin users. Check the latest studies of Riboflavin.

On Jul, 15, 2026

2,771 people reported to have side effects when taking Riboflavin.
Among them, 74 people (2.67%) died.

Among these 74 people:

What is the gender of people who died when taking Riboflavin? *

female: 17.65 %
male: 82.35 %

What is the age of people who died when taking Riboflavin? *

What are other drugs people take besides Riboflavin? *

What are other side effects people have before they died? *

Stress And Anxiety: 50 people, 67.57%
Cardiogenic Shock (inadequate circulation of blood): 49 people, 66.22%
Sepsis (a severe blood infection that can lead to organ failure and death): 49 people, 66.22%
General Physical Health Deterioration (weak health status): 46 people, 62.16%
Nausea And Vomiting: 46 people, 62.16%
Abdominal Distension: 45 people, 60.81%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 45 people, 60.81%
Constipation: 45 people, 60.81%
Ascites (accumulation of fluid in the abdominal cavity): 45 people, 60.81%
Appendicitis (inflammation of the appendix): 45 people, 60.81%

What are the existing conditions these people have? *

Constipation: 52 people, 70.27%
High Blood Cholesterol: 51 people, 68.92%
Bacterial Infection: 51 people, 68.92%
Blood Uric Acid Increased: 51 people, 68.92%
Cardiogenic Shock (inadequate circulation of blood): 51 people, 68.92%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 50 people, 67.57%
Ventricular Fibrillation (abnormally irregular heart rhythm): 48 people, 64.86%
Iron Deficiency: 48 people, 64.86%
Diabetes: 48 people, 64.86%
Neuralgia (pain in one or more nerves): 48 people, 64.86%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Riboflavin:

Riboflavin (2,869 reports)

Expand to all the drugs that have ingredients of riboflavin (vitamin b2):

Death and drugs with ingredients of riboflavin (vitamin b2) (77 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Riboflavin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Death:

Death (3,126 drugs)

Browse all the conditions that are associated with Death:

Death (3,686 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on riboflavin (vitamin b2) (the active ingredients of Riboflavin) and Riboflavin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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