Rifinah and Fatigue - a phase IV clinical study of FDA data

Summary:

Fatigue is reported as a side effect among people who take Rifinah (isoniazid; rifampin), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Rifater, and have Tuberculosis.

The phase IV clinical study analyzes which people have Fatigue when taking Rifinah. It is created by eHealthMe based on reports of 711 people who have side effects when taking Rifinah from the FDA, and is updated regularly.

What is Rifinah?

Rifinah has active ingredients of isoniazid; rifampin. eHealthMe is studying from 726 Rifinah users. Check the latest studies of Rifinah.

What is Fatigue?

Fatigue (feeling of tiredness) is found to be associated with 4,027 drugs and 6,379 conditions by eHealthMe. Check the latest studies of Fatigue.



On Jul, 13, 2026

711 people reported to have side effects when taking Rifinah.
Among them, 29 people (4.08%) have Fatigue.

Could Rifinah cause Fatigue?

Among these 29 people:

How long have people been on Rifinah when they have Fatigue? *

  • < 1 month: 33.33 %
  • 1 - 6 months: 60.0 %
  • 6 - 12 months: 6.67 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Fatigue when taking Rifinah? *

  • female: 65.52 %
  • male: 34.48 %

What is the age of people who have Fatigue when taking Rifinah? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 4.17 %
  • 20-29: 0.0 %
  • 30-39: 20.83 %
  • 40-49: 8.33 %
  • 50-59: 25.0 %
  • 60+: 41.67 %

What are other drugs people take besides Rifinah? *

  1. Rifater: 8 people, 27.59%
  2. Lyrica: 5 people, 17.24%
  3. Neupro: 5 people, 17.24%
  4. Azilect: 5 people, 17.24%
  5. Enbrel: 5 people, 17.24%
  6. Rimifon: 5 people, 17.24%
  7. Levitra: 5 people, 17.24%
  8. Myambutol: 5 people, 17.24%
  9. Augmentin: 4 people, 13.79%
  10. Humira: 3 people, 10.34%

What are other side effects people have besides Fatigue? *

  1. Malaise (a feeling of general discomfort or uneasiness): 13 people, 44.83%
  2. Nausea (feeling of having an urge to vomit): 10 people, 34.48%
  3. Pain: 9 people, 31.03%
  4. Weakness: 8 people, 27.59%
  5. Dizziness: 8 people, 27.59%
  6. Muscle Aches (muscle pain): 7 people, 24.14%
  7. Nausea And Vomiting: 7 people, 24.14%
  8. Weight Decreased: 5 people, 17.24%
  9. Delusion (a false belief or opinion): 5 people, 17.24%
  10. Melanocytic Naevus (a type of lesion that contains nevus cells (a type of melanocyte)): 5 people, 17.24%

What are the existing conditions these people have? *

  1. Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 7 people, 24.14%
  2. Parkinson's Disease: 5 people, 17.24%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 13.79%
  4. Bone Tuberculosis: 3 people, 10.34%
  5. Lymph Node Tuberculosis: 2 people, 6.90%
  6. Birth Control: 2 people, 6.90%
  7. Psoriasis (immune-mediated disease that affects the skin): 2 people, 6.90%
  8. Depression: 2 people, 6.90%
  9. Disseminated Tuberculosis: 2 people, 6.90%
  10. Essential Hypertension (primary hypertension): 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

Do you take Rifinah and have Fatigue?

- Check whether Fatigue is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rifinah:

Fatigue treatments and more:

How severe was Fatigue and when was it recovered:

Expand to all the drugs that have ingredients of isoniazid; rifampin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Rifinah:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fatigue:

Browse all the conditions that are associated with Fatigue:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on isoniazid; rifampin (the active ingredients of Rifinah) and Rifinah (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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