Ritalin and Jaw disorder - a phase IV clinical study of FDA data
Summary:
Jaw disorder is reported as a side effect among people who take Ritalin (methylphenidate hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for 1 - 2 years also take Fosamax, and have Osteoporosis.
The phase IV clinical study analyzes which people have Jaw disorder when taking Ritalin. It is created by eHealthMe based on reports of 26,179 people who have side effects when taking Ritalin from the FDA, and is updated regularly.
What is Ritalin?
Ritalin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 29,427 Ritalin users. Check the latest studies of Ritalin.
What is Jaw disorder?
Jaw disorder (jaw disease) is found to be associated with 744 drugs and 1,054 conditions by eHealthMe. Check the latest studies of Jaw disorder.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
26,179 people reported to have side effects when taking Ritalin.
Among them, 20 people (0.08%) have Jaw disorder.

Among these 20 people:
How long have people been on Ritalin when they have Jaw disorder? *
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 100 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Jaw disorder when taking Ritalin? *
- female: 75 %
- male: 25 %
What is the age of people who have Jaw disorder when taking Ritalin? *
- 0-1: 0.0 %
- 2-9: 6.67 %
- 10-19: 6.67 %
- 20-29: 0.0 %
- 30-39: 13.33 %
- 40-49: 26.67 %
- 50-59: 40.0 %
- 60+: 6.67 %
What are other drugs people take besides Ritalin? *
- Zoloft: 8 people, 40.00%
- Fosamax: 8 people, 40.00%
- Actonel: 7 people, 35.00%
- Ativan: 7 people, 35.00%
- Plaquenil: 7 people, 35.00%
- Didronel: 7 people, 35.00%
- Prevacid: 7 people, 35.00%
- Benadryl: 6 people, 30.00%
- Prograf: 6 people, 30.00%
- Reglan: 6 people, 30.00%
What are other side effects people have besides Jaw disorder? *
- Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 7 people, 35.00%
- Kidney Stones: 7 people, 35.00%
- Tooth Discoloration (a change in colour of teeth): 7 people, 35.00%
- Anaemia (lack of blood): 6 people, 30.00%
- Pain: 6 people, 30.00%
- Adverse Event: 6 people, 30.00%
- Acute Kidney Failure: 6 people, 30.00%
- Cytomegalovirus Chorioretinitis (infection of choroid and retina of the eye from virus): 6 people, 30.00%
- Lymphoproliferative Disorder (a medical condition in which the immune system makes too many white blood cells): 6 people, 30.00%
- Cytomegalovirus Oesophagitis (oesophagus infection with cytomegalo virus): 6 people, 30.00%
What are the existing conditions these people have? *
- Osteoporosis (bones weak and more likely to break): 7 people, 35.00%
- Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 4 people, 20.00%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 20.00%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 10.00%
- Stress And Anxiety: 1 person, 5.00%
- Pain: 1 person, 5.00%
- Neoplasm Malignant (cancer tumour): 1 person, 5.00%
- Muscle Spasms (muscle contraction): 1 person, 5.00%
- Multiple Myeloma (cancer of the plasma cells): 1 person, 5.00%
- Hyperchlorhydria (gastric acid levels are higher in stomach): 1 person, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Ritalin and have Jaw disorder?
- Check whether Jaw disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Ritalin:
- Ritalin (29,427 reports)
Jaw disorder treatments and more:
- Jaw disorder (9,029 reports)
How severe was Jaw disorder and when was it recovered:
Expand to all the drugs that have ingredients of methylphenidate hydrochloride:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ritalin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Jaw disorder:
- Jaw disorder (744 drugs)
Browse all the conditions that are associated with Jaw disorder:
- Jaw disorder (1,054 conditions)
Related publications that referenced our studies
- Coskun M, Adak I, "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2017 Oct .
- Yektas ?, Samurcu ND, Tufan AE, "Loss of Eyebrows (Madarosis) After Use of Long-Acting Methylphenidate: Case Report", Journal of Clinical Psychopharmacology, 2017 Aug .
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
- Adak, I., & Coskun, M. , "Symptomatic cholelithiasis associated with combined use of methylphenidate and fluoxetine in an otherwise healthy adolescent girl", Psychiatry and Clinical Psychopharmacology, 2014 Jan .
- Coskun, M., & Adak, I. , "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2014 Jan .
- Yalcin O, Aslan AA, Sari BA, Turkbay T, "Possible methylphenidate related hoarseness and disturbances of voice quality: two pediatric cases", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2012 Sep .
- Lufi D, Bucherman M, Akita M, Cohen R, Sibani C, "The effect of methylphenidate on speech patterns of children with attention deficit disorder", Journal of Behavioral Health, 2012 Jan .
- Coskun M, Adak I, "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2017 Oct .
- Yektas ?, Samurcu ND, Tufan AE, "Loss of Eyebrows (Madarosis) After Use of Long-Acting Methylphenidate: Case Report", Journal of Clinical Psychopharmacology, 2017 Aug .
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
- Adak, I., & Coskun, M. , "Symptomatic cholelithiasis associated with combined use of methylphenidate and fluoxetine in an otherwise healthy adolescent girl", Psychiatry and Clinical Psychopharmacology, 2014 Jan .
- Coskun, M., & Adak, I. , "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2014 Jan .
- Yalcin O, Aslan AA, Sari BA, Turkbay T, "Possible methylphenidate related hoarseness and disturbances of voice quality: two pediatric cases", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2012 Sep .
- Lufi D, Bucherman M, Akita M, Cohen R, Sibani C, "The effect of methylphenidate on speech patterns of children with attention deficit disorder", Journal of Behavioral Health, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on methylphenidate hydrochloride (the active ingredients of Ritalin) and Ritalin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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