Ritalin and Ligament disorder - a phase IV clinical study of FDA data

Summary:

Ligament disorder is reported as a side effect among people who take Ritalin (methylphenidate hydrochloride), especially for people who are female, 50-59 old, also take Xyrem, and have Impaired driving ability.

The phase IV clinical study analyzes which people have Ligament disorder when taking Ritalin. It is created by eHealthMe based on reports of 26,179 people who have side effects when taking Ritalin from the FDA, and is updated regularly.

What is Ritalin?

Ritalin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 29,427 Ritalin users. Check the latest studies of Ritalin.

What is Ligament disorder?

Ligament disorder (disease of ligament) is found to be associated with 206 drugs and 259 conditions by eHealthMe. Check the latest studies of Ligament disorder.

On Jul, 16, 2026

26,179 people reported to have side effects when taking Ritalin.
Among them, 12 people (0.05%) have Ligament disorder.

Among these 12 people:

What is the gender of people who have Ligament disorder when taking Ritalin? *

female: 58.33 %
male: 41.67 %

What is the age of people who have Ligament disorder when taking Ritalin? *

What are other drugs people take besides Ritalin? *

What are other side effects people have besides Ligament disorder? *

Joint Pain: 11 people, 91.67%
Headache (pain in head): 10 people, 83.33%
Pain In Extremity: 7 people, 58.33%
Infection: 7 people, 58.33%
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue): 7 people, 58.33%
Diarrhea: 7 people, 58.33%
Ligament Sprain (ligament stretched): 7 people, 58.33%
Night Sweats (sweating in night): 7 people, 58.33%
Bone Density Decreased: 7 people, 58.33%
Acne (skin problems that cause pimples): 7 people, 58.33%

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 58.33%
Impaired Driving Ability: 7 people, 58.33%
Joint Pain: 3 people, 25.00%
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 3 people, 25.00%
Abdominal Pain Upper: 3 people, 25.00%
Blood Testosterone Decreased: 3 people, 25.00%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 25.00%
High Blood Cholesterol: 3 people, 25.00%
High Blood Pressure: 3 people, 25.00%
Indigestion: 3 people, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Ritalin and have Ligament disorder?

- Check whether Ligament disorder is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ritalin:

Ritalin (29,427 reports)

Browse all side effects of Ritalin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ligament disorder:

Ligament disorder (206 drugs)

Browse all the conditions that are associated with Ligament disorder:

Ligament disorder (259 conditions)

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on methylphenidate hydrochloride (the active ingredients of Ritalin) and Ritalin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.