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Ritalin and Synovial cyst - a phase IV clinical study of FDA data

Summary:

Synovial cyst is reported as a side effect among people who take Ritalin (methylphenidate hydrochloride), especially for people who are female, 60+ old, also take Zometa, and have Metastases to bone.

The phase IV clinical study analyzes which people have Synovial cyst when taking Ritalin. It is created by eHealthMe based on reports of 26,179 people who have side effects when taking Ritalin from the FDA, and is updated regularly.

What is Ritalin?

Ritalin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 29,427 Ritalin users. Check the latest studies of Ritalin.

What is Synovial cyst?

Synovial cyst (cyst of joint filled with synovial fluid) is found to be associated with 778 drugs and 560 conditions by eHealthMe. Check the latest studies of Synovial cyst.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

26,179 people reported to have side effects when taking Ritalin.
Among them, 51 people (0.19%) have Synovial cyst.

Could Ritalin cause Synovial cyst?

Among these 51 people:

What is the gender of people who have Synovial cyst when taking Ritalin? *

  • female: 65.96 %
  • male: 34.04 %

What is the age of people who have Synovial cyst when taking Ritalin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 2.38 %
  • 30-39: 14.29 %
  • 40-49: 7.14 %
  • 50-59: 19.05 %
  • 60+: 57.14 %

What are other drugs people take besides Ritalin? *

  1. Zometa: 34 people, 66.67%
  2. Ambien: 33 people, 64.71%
  3. Cephalexin: 33 people, 64.71%
  4. Miacalcin: 33 people, 64.71%
  5. Neurontin: 27 people, 52.94%
  6. Protonix: 26 people, 50.98%
  7. Concerta: 23 people, 45.10%
  8. Flexeril: 19 people, 37.25%
  9. Gentamicin: 18 people, 35.29%
  10. Meloxicam: 18 people, 35.29%

What are other side effects people have besides Synovial cyst? *

  1. Joint Pain: 40 people, 78.43%
  2. Foot Fracture: 36 people, 70.59%
  3. Dyspnea (difficult or laboured breathing): 34 people, 66.67%
  4. Osteonecrosis Of Jaw (death of bone of jaw): 34 people, 66.67%
  5. Headache (pain in head): 33 people, 64.71%
  6. Metastases To Bone (cancer spreads to bone): 33 people, 64.71%
  7. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 33 people, 64.71%
  8. Anaemia (lack of blood): 33 people, 64.71%
  9. Osteoporosis (bones weak and more likely to break): 33 people, 64.71%
  10. Tendon Disorder (disease of tendon): 32 people, 62.75%

What are the existing conditions these people have? *

  1. Metastases To Bone (cancer spreads to bone): 18 people, 35.29%
  2. Pain: 7 people, 13.73%
  3. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 7 people, 13.73%
  4. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 7.84%
  5. Drowsiness: 2 people, 3.92%
  6. Renal Cell Carcinoma (a kidney cancer): 1 person, 1.96%
  7. Prostate Cancer: 1 person, 1.96%
  8. Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 1.96%
  9. Indigestion: 1 person, 1.96%

* Approximation only. Some reports may have incomplete information.

Do you take Ritalin and have Synovial cyst?

- Check whether Synovial cyst is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ritalin:

Synovial cyst treatments and more:

How severe was Synovial cyst and when was it recovered:

Expand to all the drugs that have ingredients of methylphenidate hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ritalin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Synovial cyst:

Browse all the conditions that are associated with Synovial cyst:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on methylphenidate hydrochloride (the active ingredients of Ritalin) and Ritalin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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