Rituxan and Interstitial nephritis - a phase IV clinical study of FDA data

Summary:

Interstitial nephritis is reported as a side effect among people who take Rituxan (rituximab), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Prilosec, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Interstitial nephritis when taking Rituxan. It is created by eHealthMe based on reports of 64,282 people who have side effects when taking Rituxan from the FDA, and is updated regularly.

What is Rituxan?

Rituxan has active ingredients of rituximab. It is often used in rheumatoid arthritis. eHealthMe is studying from 64,792 Rituxan users. Check the latest studies of Rituxan.

What is Interstitial nephritis?

Interstitial nephritis (inflammation of the kidney) is found to be associated with 1,085 drugs and 1,568 conditions by eHealthMe. Check the latest studies of Interstitial nephritis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

64,282 people reported to have side effects when taking Rituxan.
Among them, 14 people (0.02%) have Interstitial nephritis.

Could Rituxan cause Interstitial nephritis?

Among these 14 people:

How long have people been on Rituxan when they have Interstitial nephritis? *

What is the gender of people who have Interstitial nephritis when taking Rituxan? *

female: 46.15 %
male: 53.85 %

What is the age of people who have Interstitial nephritis when taking Rituxan? *

What are other drugs people take besides Rituxan? *

Prilosec: 8 people, 57.14%
Protonix: 7 people, 50.00%
Nexium 24hr: 7 people, 50.00%
Nexium: 7 people, 50.00%
Hydrocodone Bitartrate And Acetaminophen: 5 people, 35.71%
Cimetidine: 5 people, 35.71%
Klor-Con: 5 people, 35.71%
Kytril: 5 people, 35.71%
Ondansetron: 5 people, 35.71%
Novolog: 5 people, 35.71%

What are other side effects people have besides Interstitial nephritis? *

Chronic Kidney Disease: 8 people, 57.14%
Acute Kidney Failure: 6 people, 42.86%
Hypertensive Cardiomegaly (enlarged heart due to hypertension): 5 people, 35.71%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 35.71%
Nephropathy (damage to or disease of a kidney): 5 people, 35.71%
Depression: 5 people, 35.71%
Dementia (madness): 5 people, 35.71%
Cystitis Interstitial (unknown cause characterized by bladder pain): 5 people, 35.71%
Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 5 people, 35.71%
Cardiac Failure Congestive: 5 people, 35.71%

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 42.86%
Nausea (feeling of having an urge to vomit): 5 people, 35.71%
Constipation: 5 people, 35.71%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 3 people, 21.43%
Flatulence (flatus expelled through the anus): 3 people, 21.43%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 3 people, 21.43%
Kidney Transplant Rejection: 3 people, 21.43%
Transplant Rejection (a transplant material is not worked): 3 people, 21.43%
Bipolar Disorder (mood disorder): 2 people, 14.29%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Rituxan and have Interstitial nephritis?

- Check whether Interstitial nephritis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rituxan:

Rituxan (64,792 reports)

Browse all side effects of Rituxan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Interstitial nephritis:

Interstitial nephritis (1,085 drugs)

Browse all the conditions that are associated with Interstitial nephritis:

Interstitial nephritis (1,568 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on rituximab (the active ingredients of Rituxan) and Rituxan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.