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Robitussin and Stroke - a phase IV clinical study of FDA data

Summary:

Stroke is reported as a side effect among people who take Robitussin (guaifenesin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Tylenol, and have Birth control.

The phase IV clinical study analyzes which people have Stroke when taking Robitussin. It is created by eHealthMe based on reports of 3,522 people who have side effects when taking Robitussin from the FDA, and is updated regularly.

What is Robitussin?

Robitussin has active ingredients of guaifenesin. eHealthMe is studying from 3,532 Robitussin users. Check the latest studies of Robitussin.

What is Stroke?

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) is found to be associated with 2,310 drugs and 3,029 conditions by eHealthMe. Check the latest studies of Stroke.

On Jul, 13, 2026

3,522 people reported to have side effects when taking Robitussin.
Among them, 60 people (1.7%) have Stroke.

Could Robitussin cause Stroke?

Among these 60 people:

How long have people been on Robitussin when they have Stroke? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Stroke when taking Robitussin? *

  • female: 76.92 %
  • male: 23.08 %

What is the age of people who have Stroke when taking Robitussin? *

  • 0-1: 0.0 %
  • 2-9: 8.89 %
  • 10-19: 0.0 %
  • 20-29: 15.56 %
  • 30-39: 0.0 %
  • 40-49: 13.33 %
  • 50-59: 17.78 %
  • 60+: 44.44 %

What are other drugs people take besides Robitussin? *

  1. Vitamin D3: 15 people, 25.00%
  2. Tylenol: 15 people, 25.00%
  3. Lasix: 13 people, 21.67%
  4. Acetaminophen: 10 people, 16.67%
  5. Atorvastatin Calcium: 9 people, 15.00%
  6. Sodium Chloride: 9 people, 15.00%
  7. Vitamin B12: 9 people, 15.00%
  8. Ondansetron: 8 people, 13.33%
  9. Albuterol: 8 people, 13.33%
  10. Gabapentin: 8 people, 13.33%

What are other side effects people have besides Stroke? *

  1. Head Injury: 17 people, 28.33%
  2. Fall: 15 people, 25.00%
  3. Migraine (headache): 12 people, 20.00%
  4. Headache (pain in head): 12 people, 20.00%
  5. Nausea (feeling of having an urge to vomit): 12 people, 20.00%
  6. Back Pain: 12 people, 20.00%
  7. Dizziness: 12 people, 20.00%
  8. Sinusitis (inflammation of sinus): 11 people, 18.33%
  9. Heart Attack: 11 people, 18.33%
  10. Depression: 9 people, 15.00%

What are the existing conditions these people have? *

  1. Birth Control: 7 people, 11.67%
  2. Multiple Myeloma (cancer of the plasma cells): 6 people, 10.00%
  3. Constipation: 6 people, 10.00%
  4. Immunodeficiency Common Variable: 6 people, 10.00%
  5. High Blood Pressure: 4 people, 6.67%
  6. Stress And Anxiety: 4 people, 6.67%
  7. Cough: 4 people, 6.67%
  8. Upper Respiratory Tract Infection: 3 people, 5.00%
  9. Pain: 3 people, 5.00%
  10. Nasopharyngitis (inflammation of the nasopharynx): 3 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Robitussin and have Stroke?

- Check whether Stroke is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Robitussin:

Stroke treatments and more:

How severe was Stroke and when was it recovered:

Expand to all the drugs that have ingredients of guaifenesin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Robitussin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stroke:

Browse all the conditions that are associated with Stroke:

How the study uses the data?

The study uses data from the FDA. It is based on guaifenesin (the active ingredients of Robitussin) and Robitussin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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