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Rocephin and Rheumatoid arthritis - a phase IV clinical study of FDA data

Summary:

Rheumatoid arthritis is reported as a side effect among people who take Rocephin (ceftriaxone sodium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Lasix, and have Bone density decreased.

The phase IV clinical study analyzes which people have Rheumatoid arthritis when taking Rocephin. It is created by eHealthMe based on reports of 15,458 people who have side effects when taking Rocephin from the FDA, and is updated regularly.

What is Rocephin?

Rocephin has active ingredients of ceftriaxone sodium. It is often used in infection. eHealthMe is studying from 15,665 Rocephin users. Check the latest studies of Rocephin.

What is Rheumatoid arthritis?

Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints) is found to be associated with 1,671 drugs and 2,130 conditions by eHealthMe. Check the latest studies of Rheumatoid arthritis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 12, 2026

15,458 people reported to have side effects when taking Rocephin.
Among them, 41 people (0.27%) have Rheumatoid arthritis.

Could Rocephin cause Rheumatoid arthritis?

Among these 41 people:

How long have people been on Rocephin when they have Rheumatoid arthritis? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Rheumatoid arthritis when taking Rocephin? *

  • female: 50 %
  • male: 50 %

What is the age of people who have Rheumatoid arthritis when taking Rocephin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 6.9 %
  • 30-39: 6.9 %
  • 40-49: 3.45 %
  • 50-59: 10.34 %
  • 60+: 72.41 %

What are other drugs people take besides Rocephin? *

  1. Lasix: 19 people, 46.34%
  2. Digoxin: 18 people, 43.90%
  3. Levaquin: 18 people, 43.90%
  4. Neurontin: 17 people, 41.46%
  5. Aredia: 16 people, 39.02%
  6. Zometa: 16 people, 39.02%
  7. Prilosec: 16 people, 39.02%
  8. Prednisone: 15 people, 36.59%
  9. Coumadin: 15 people, 36.59%
  10. Casodex: 14 people, 34.15%

What are other side effects people have besides Rheumatoid arthritis? *

  1. Pain: 23 people, 56.10%
  2. Stress And Anxiety: 21 people, 51.22%
  3. Hypotension (abnormally low blood pressure): 18 people, 43.90%
  4. Oedema Peripheral (superficial swelling): 18 people, 43.90%
  5. Anaemia (lack of blood): 17 people, 41.46%
  6. Dehydration (dryness resulting from the removal of water): 17 people, 41.46%
  7. Death: 17 people, 41.46%
  8. Hearing Loss: 16 people, 39.02%
  9. Gallstones (stone formation by bile component): 16 people, 39.02%
  10. Fainting (loss of consciousness and postural tone): 16 people, 39.02%

What are the existing conditions these people have? *

  1. Bone Density Decreased: 10 people, 24.39%
  2. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 9 people, 21.95%
  3. Bone Loss: 4 people, 9.76%
  4. Bipolar Disorder (mood disorder): 3 people, 7.32%
  5. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 4.88%
  6. Pain: 2 people, 4.88%
  7. Headache (pain in head): 2 people, 4.88%
  8. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 2.44%
  9. Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 2.44%
  10. Borrelia Infection (infectious disease caused by bacteria belonging to the genus borrelia): 1 person, 2.44%

* Approximation only. Some reports may have incomplete information.

Do you take Rocephin and have Rheumatoid arthritis?

- Check whether Rheumatoid arthritis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rocephin:

Rheumatoid arthritis treatments and more:

How severe was Rheumatoid arthritis and when was it recovered:

Expand to all the drugs that have ingredients of ceftriaxone sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Rocephin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rheumatoid arthritis:

Browse all the conditions that are associated with Rheumatoid arthritis:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on ceftriaxone sodium (the active ingredients of Rocephin) and Rocephin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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