Roxicodone and Atrial fibrillation/flutter - a phase IV clinical study of FDA data

Summary:

Atrial fibrillation/flutter is reported as a side effect among people who take Roxicodone (oxycodone hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zofran, and have Constipation.

The phase IV clinical study analyzes which people have Atrial fibrillation/flutter when taking Roxicodone. It is created by eHealthMe based on reports of 19,861 people who have side effects when taking Roxicodone from the FDA, and is updated regularly.

What is Roxicodone?

Roxicodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 20,099 Roxicodone users. Check the latest studies of Roxicodone.

What is Atrial fibrillation/flutter?

Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles) is found to be associated with 2,364 drugs and 3,842 conditions by eHealthMe. Check the latest studies of Atrial fibrillation/flutter.

On Jul, 13, 2026

19,861 people reported to have side effects when taking Roxicodone.
Among them, 87 people (0.44%) have Atrial fibrillation/flutter.

Could Roxicodone cause Atrial fibrillation/flutter?

Among these 87 people:

How long have people been on Roxicodone when they have Atrial fibrillation/flutter? *

What is the gender of people who have Atrial fibrillation/flutter when taking Roxicodone? *

female: 52.38 %
male: 47.62 %

What is the age of people who have Atrial fibrillation/flutter when taking Roxicodone? *

What are other drugs people take besides Roxicodone? *

What are other side effects people have besides Atrial fibrillation/flutter? *

Anaemia (lack of blood): 21 people, 24.14%
Fatigue (feeling of tiredness): 19 people, 21.84%
Hypotension (abnormally low blood pressure): 16 people, 18.39%
Thrombocytopenia (decrease of platelets in blood): 15 people, 17.24%
Pneumonia: 15 people, 17.24%
Sepsis (a severe blood infection that can lead to organ failure and death): 14 people, 16.09%
Acute Respiratory Failure: 12 people, 13.79%
Nausea (feeling of having an urge to vomit): 12 people, 13.79%
Nausea And Vomiting: 12 people, 13.79%
Chest Pain: 12 people, 13.79%

What are the existing conditions these people have? *

Constipation: 18 people, 20.69%
Nausea (feeling of having an urge to vomit): 16 people, 18.39%
Insomnia (sleeplessness): 10 people, 11.49%
Stress And Anxiety: 9 people, 10.34%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 9 people, 10.34%
High Blood Pressure: 8 people, 9.20%
Lung Cancer - Non-Small Cell (lung cancer): 6 people, 6.90%
Fever: 6 people, 6.90%
Depression: 6 people, 6.90%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 6 people, 6.90%

* Approximation only. Some reports may have incomplete information.

Do you take Roxicodone and have Atrial fibrillation/flutter?

- Check whether Atrial fibrillation/flutter is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Roxicodone:

Roxicodone (20,099 reports)

Browse all side effects of Roxicodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Atrial fibrillation/flutter:

Atrial fibrillation/flutter (2,364 drugs)

Browse all the conditions that are associated with Atrial fibrillation/flutter:

Atrial fibrillation/flutter (3,842 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Roxicodone) and Roxicodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.